Calcium-sodium ethylenediaminetetraacetate (Calcium disodium ethylene diamine tetra-acetate, Calcium disodium EDTA, calcium disodium salt of ethylenediaminetetraacetic acid, EDTA, E385) is a dietary supplement of the antioxidant group.

Organic matter EDTA is known for its ability to bind transition metal ions such as iron, copper, and cobalt. Its molecule wraps its active groups around them like a ping-pong ball. This property is used for preserving mayonnaise: egg white always contains iron ions, which, without EDTA, are able to catalyze the lipid oxidation reaction. EDTA itself is not a useful substance, especially for young children, although it is not poisonous. But its concentration in mayonnaise is so small that it can not bring harm.

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