Duspatalin: instructions for use

Duspatalin is a myotropic antispasmodic that helps to eliminate spasm of the smooth muscles of the intestine. In this case, the natural contractions of the intestinal wall will not be disturbed. Therefore, the drug can be taken without fear that the process of moving feces through the intestines will stop. The drug is aimed solely at eliminating pain.

The therapeutic effect of Duspatalin allows it to be used to relieve intestinal colic, irritable bowel syndrome, biliary colic, pain in the stomach, regardless of their etiology. The drug is prescribed for functional disorders of the digestive system.

General characteristics

Duspatalin is manufactured in the Netherlands by Abbot Healthcare Products, B.V. You can buy the drug in the form of tablets of 135 g and capsules of 200 mg. The capsule form contains a larger amount of the main active ingredient compared to tablets. Due to this, you can achieve a lasting effect from taking the drug. Therefore, on the packaging with capsules there is the word “retard”, which means “slow down” in English.

The capsules are covered with a dense shell based on gelatin, inside each such capsule contains white granules. Capsule markings: “245”, “S”, “7”. You can purchase a package containing 10, 20, 30, 50, 60 and 90 capsules.

The tablets are round and white in color. They can be purchased in the same quantity as the capsules, as well as in packs of 15, 40, 100 and 120 pieces.

Regardless of the form of release, the main active ingredient remains the same – it is mebeverine. However, the auxiliary components in capsules and tablets are different. Their comparative characteristics are presented in the table.

The effect of taking

Taking Duspatalin allows you to relieve spasm from the smooth muscles of the digestive organs. This is due to the elimination of tension, which provokes the appearance of pain. Since it is in the intestines that the most smooth muscles are concentrated, the drug has the most pronounced effect on it. The elimination of hypertonicity occurs without affecting the peristalsis of the organ. Therefore, feces pass through the intestines without any slowdowns. That is, Duspatalin has a targeted effect on the smooth muscles of the intestine, eliminating pain. In parallel, the sphincter of Oddi is relaxed, which normalizes the outflow of bile and provides an analgesic effect in biliary colic.

If the activity of the smooth muscles of the intestine is increased, then taking Duspatalin will bring it back to normal. However, the peristalsis of the organ will not be completely stopped, that is, its reflex hypotension will not occur.

After passing the drug through the organs of the digestive system, it enters the intestines, from where it is transferred to the liver with the blood stream. There, certain biochemical reactions are triggered, and the medicinal substance decomposes to the state of metabolites. In this form, it is excreted from the body with urine. From the capsule, the main active substance is not released as quickly as from tablets, so the therapeutic effect is extended for 16 hours. And for this it will be enough to take the drug once.

When should Duspatalin be used?

Indications for taking the drug:

• Spasm-type pain with localization in the epigastric region.

• Intestinal and biliary colic.

• Irritable Bowel Syndrome.

• Disorders in the gallbladder.

• Postponed surgery for resection of the gallbladder.

• Spasms of the smooth muscles of the digestive system against the background of pathologies of other organs (pain in pancreatitis or cholecystitis).

• Pain provoked by a functional disorder of the digestive system.

• Pain, discomfort and spasm in the intestines of a different etiology.

Instructions for use

Duspatalin in the form of tablets

The drug is not crushed before ingestion, washed down with plain water. The drug should be taken 30 minutes before meals.

It is permissible to drink three tablets per day: in the morning, at lunchtime and in the evening. You should stop taking the drug after you feel better, that is, as soon as the pain stops.

The drug should not be abruptly discontinued. You must adhere to the following scheme:

• The first 7 days of withdrawal: the drug is taken 1 tablet in the morning and at lunchtime, and 1/2 tablet is drunk in the evening.

• From 7 to 14 days, they drink a whole tablet in the morning and evening.

• From 14 to 21 days, take a whole tablet in the morning, and 1/2 of the drug in the evening.

• From 21 to 28 days take the drug 1 tablet in the morning.

According to this scheme, it is proposed to cancel the drug by leading domestic clinicians who are engaged in the treatment of diseases of the digestive system.

Depending on the individual case, the withdrawal schedule may be reviewed by the attending physician. So, if after reducing the dose of the drug, the patient feels well, then it is possible to reduce the scheme of its withdrawal to 14 days. If the patient feels unsatisfactory when the dose is reduced by 1 tablet, then it is necessary to reduce it by 1/2 tablet. The patient should be monitored for at least 2 days.

Most experts recommend reducing the dosage by 1/2 tablet. If there is a need for a faster withdrawal of the drug, then after 2 days you can once again reduce the dosage by 1/2 tablet. Provided that the patient’s well-being does not worsen, such a scheme should be maintained until the end of the week (the countdown starts from the first day of dose reduction). If the patient begins to feel worse, then they switch to the classical scheme for refusing the drug. With a positive trend, you can continue. That is, at the beginning of each subsequent week, it will be necessary to reduce the dose by 1/2 tablet, and after 2 days by another 1/2 tablet.

Abrupt withdrawal of the drug is unacceptable.

Duspatalin capsules

Capsules are not chewed, swallowed whole with plain water. The drug is taken 20 minutes before meals, 2 times a day.

The course of treatment is determined by the complete disappearance of pain and spasms. After that, you can begin to gradually reduce the dosage of the drug. Just like tablets, capsules should not be abruptly discarded. The dosage should be reduced gradually. Drug withdrawal scheme:

1. The first 7-14 days you need to take 1 capsule in the morning.

2. After 7-14 days, the drug should be discontinued.

To determine for how long it is necessary to stop taking the capsules – 7 or 14 days in advance, after a weekly intake of 1 capsule per day, take a two-day break. If during this time the state of health does not worsen, then further treatment can be completely abandoned. Provided that the patient begins to feel worse, the course of therapy is extended for another 7 days, continuing to take 1 capsule in the morning. Then the drug is abandoned altogether.

Overdose

If a person has taken too much of the drug, this will lead to an increase in nervous excitability. To neutralize the effect of the drug, you should wash the stomach and take activated charcoal inside. In the future, the patient is shown symptomatic treatment.

Co-administration with other drugs

Duspatalin can be taken simultaneously with other drugs.

It should be noted that Duspatalin can provoke dizziness, therefore, during the therapeutic course, it is highly desirable to abandon activities that require increased concentration.

Treatment of children with Duspatalin

At the age of less than 12 years, taking Duspatalin is contraindicated.

If the child is already 12 years old, then the doctor may prescribe him Duspatalin to eliminate spasm and pain in the intestines and other organs of the digestive system.

Doctors recommend taking the drug to children with the following disorders:

• Heaviness and pain in the abdomen.

• Intestinal colic.

• Abdominal pain due to overeating.

• Abdominal pain due to nervous tension.

• Irritable bowel syndrome in a child.

• Pain with inaccuracies in nutrition. So, if a teenager suffers from abdominal pain due to functional indigestion (the child ate a lot of muffin, fast food or drank a lot of sparkling water), then he should immediately take a Duspatalin capsule. One more capsule is drunk in the evening. The next day, treatment can be stopped, provided that the state of health has stabilized. If the child continues to feel unwell, then the drug can be continued. When treatment is delayed for more than 7 days, the drug will need to be discontinued gradually, according to the scheme recommended for an adult.

So, only a doctor can prescribe Duspatalin courses for a child. As a rule, such a treatment regimen is rarely practiced. It is indicated for violations in the outflow of bile. Until the child’s condition stabilizes, he will need to take two capsules of the drug per day. The withdrawal of the drug lasts for 10 days, during which time the child receives 1 capsule per day. Then they refuse to take the drug at all.

Taking Duspatalin during pregnancy

Antispasmodics are prescribed during pregnancy with increased uterine tone. For this purpose, women are prescribed No-shpu. However, when the spasm passes to the smooth muscles of the intestine, it is better to use Duspatalin. With hypertonicity of the uterus, this drug will be ineffective.

You should also use Duspatalin during pregnancy if there is a spasm of the sphincter of Oddi. This leads to a violation of the outflow of bile and pain in the abdomen.

Studies have been conducted regarding the effects of Duspatalin on the fetus. During the experiments, it was possible to establish that the drug does not have a negative effect on the child in the womb. Therefore, if the doctor recommends taking the drug during pregnancy, then the benefits of prescribing it cover all possible risks. Self-administration of Duspatalin is unacceptable, consultation with a specialist is mandatory.

During pregnancy, you can only take capsules, tablets during this period are strictly contraindicated. Duspatalin should not be combined with other antispasmodics, for example, with Papaverine or No-shpa.

The dose for pregnant women is 2 capsules per day. One of them is taken in the morning, and the second in the evening. The course of treatment continues until there is a noticeable improvement in well-being. Cancel the drug gradually, for this, for 14 days, drink 1 capsule per day. After 14 days, the drug is completely abandoned.

Duspatalin is often prescribed to women who, even before the moment of conception, suffered from spasms of the sphincter of Oddi. Often this condition accompanies chronic inflammation of the pancreas or occurs after surgery for resection of the gallbladder.

If a woman has a spasm of the smooth muscles of the intestine against the background of emotional overstrain, or as a result of errors in the diet, then you can take the drug one-time. The cancellation scheme is not practiced in this case.

Taking Duspatalin for pancreatitis

Duspatalin is an effective remedy for pain relief in pancreatitis. This process is always accompanied by a violation of the outflow of pancreatic juice and spasm of the sphincter of Oddi. This problem can be solved by taking Duspatalin.

The excretory ducts against the background of inflammation of the pancreas are spasmodic, and the juice is released in large quantities. As a result, the gland begins to digest itself with its own enzymes. To prevent such a situation, it is necessary to expand the excretory ducts, removing spasm from them. It is Duspatalin that copes with this problem better than other antispasmodics.

The drug is prescribed for a slight exacerbation of pancreatitis, which improves the patient’s well-being. For treatment, capsules are used, taking them twice a day, 1 piece each (morning and evening).

Treatment should continue until the patient’s condition stabilizes. Then the drug is gradually canceled.

Duspatalin can also be used to prevent exacerbation of inflammation of the pancreas, provided that the disease has a chronic course. To do this, take 14 capsule 1 times a day for 2 days, and then take one capsule a day for another 7 days. In the future, the use of the drug is completely abandoned.

The combination of Duspatalin with alcoholic beverages

You can not combine the drug and alcohol. Alcoholic beverages increase vasospasm, smooth muscles of the intestine and pancreatic ducts. Therefore, the effect of taking the drug will not be achieved, or it will be minimal.

Side effects of the drug

Side effects while taking the drug are extremely rare. A study was conducted involving 8 antispasmodics that are used to treat irritable bowel syndrome. During the experiment, it was possible to establish that Duspatalin of all medicines gives fewer side effects.

However, some patients may experience the following problems:

• Dizziness;

• Skin rashes;

• Quincke’s edema and swelling of the face;

• Allergy in the form of exanthema;

• Itchy skin;

• Headache;

• diarrhea or constipation;

• Nausea.

Противопоказания

Duspatalin should not be prescribed to patients who have hypersensitivity to the components of the drug, or an allergic reaction to its reception is observed.

During gestation and during lactation, the drug should be used with caution.

Analogues

Russian pharmaceutical companies produce analogues and synonyms of the drug Duspatalin. Synonymous preparations contain mebeverine in their composition, and analogues have other components, but a similar therapeutic effect.

Drugs-synonyms of Duspatalin:

• Niaspam capsules.

• Sparex capsules.

• Mebeverine in the form of tablets.

Duspatalin analogues:

• Trigan in the form of tablets and in the form of injections for intramuscular administration.

• Trimedat tablets.

• Spaskuprel tablets.

• Dibazol tablets.

• Buscopan tablets.

• Bendazole tablets.

• Dicetel tablets.

• No-shpa in tablets.

• Drotaverine tablets.

• Papaverine in tablets.

Inexpensive analogues of Duspatalin

Duspatalin analogues for the treatment of irritable bowel syndrome at a lower price: Sparex, Trigan and Niaspam.

If we consider inexpensive antispasmodics, then these include: Drotaverine, No-shpa, Papaverine, Ditsetel.

Reviews

Patients who received Duspatalin leave more positive feedback about him. They indicate that the drug allows you to quickly cope with intestinal and gastric colic, eliminate functional indigestion, abdominal pain after overeating.

Patients with irritable bowel syndrome note that Duspatalin makes it possible to get rid of pain, adjust stool, and reduce bloating. Patients treated with antibiotics often suffer from dysbacteriosis, against which severe abdominal pain manifests itself. Duspatalin copes with this problem perfectly. Pain begins to subside after half an hour after the first dose of the drug. Moreover, the capsules differ in prolonged action.

Duspatalin has positive feedback from patients suffering from inflammation of the pancreas and gallbladder. The drug quickly relieves spasm, which leads to the normalization of the patient’s condition. Even with exacerbation of pancreatitis and cholecystitis, it is possible to completely cope with pain in 2-3 days. Patients with chronic pathologies take Duspatalin for prophylactic purposes and note its high efficiency in terms of preventing the development of relapses.

Negative reviews about Duspatalin are extremely rare. They boil down to the fact that the drug did not allow to eliminate pain during exacerbation of inflammation of the pancreas or gallbladder. However, one should not expect a lightning-fast solution to the problem, since 2-3 days should pass for pain relief, and not several hours. Therefore, such reviews can be considered not entirely justified.

Some people become disillusioned with the drug, taking it off-label. Often patients indicate that Duspatalin did not help to cope with gastritis or stomach ulcers. But this drug is not intended for the treatment of these diseases. Duspatalin is an antispasmodic and its main action is to reduce pain.

Expert Reviews

Practicing gynecologists note that Duspatalin allows you to get rid of intestinal colic in pregnant women, regardless of the nature of their occurrence.

Therapists and gastroenterologists indicate that Duspatalin can be successfully used in the treatment of irritable bowel syndrome, pancreatitis, cholecystitis, as well as to get rid of negative symptoms that occur with functional digestive disorders.

Doctors indicate that it is impossible to use Duspatalin as a monocomponent for pancreatitis. The drug should be included in the complex therapy regimen. Otherwise, recovery will not be possible.

What to choose: Duspatalin or Trimedat?

Trimedat and Duspatalin have a similar therapeutic effect, since both of these drugs can relieve muscle spasm. The difference lies in the fact that Trimedat has a wider spectrum of action compared to Duspatalin, so it is used to treat severe pathologies of the digestive system. If the patient has chronic pancreatitis or cholecystitis, or an exacerbation of the disease has occurred, then Duspatalin can be taken.

In any case, the doctor should prescribe this or that drug, starting from the individual characteristics of the patient’s body. Trimedat is more suitable for one patient, and Duspatalin for others.

What to choose: Duspatalin or Dicetel?

Dicetel has a less pronounced effect compared to Duspatalin. The drug will not completely remove the spasm from the ducts of the pancreas and gallbladder, which occurs against the background of inflammation of these organs. In addition, taking Dicetel is associated with a greater risk of developing allergic reactions than taking Duspatalin.

However, if a person has an indigestion caused by an irrational approach to nutrition, Ditsetel can be used. In this case, the drug will cope well with the task of anesthesia.

What is the price of duspatalin?

Duspatalin is an imported drug, so its price cannot be low. The average cost for a package of a drug in 30 capsules is 380-465 rubles, depending on the outlet.