Contents
Dobenox contains calcium dobesylate monohydrate, which has the properties of reducing the permeability of capillaries and increasing their strength. It is an active substance that also prevents the formation of exudates and improves microcirculation. Calcium dobesylate, by reducing blood viscosity and deposition of platelets on vessel walls, prevents blood stagnation and thrombus formation, enhances collagen synthesis and stimulates blood hemodynamic parameters, increases blood flow through peripheral tissues, and inhibits platelet aggregation. Thanks to its properties, it supports the relief of pain and the feeling of heaviness and fatigue in the lower limbs, and also supports the treatment of edema and varicose veins.
Dobenox – indications for use
Dobenox can be used in the treatment of chronic venous insufficiency of the lower extremities (pain and night cramps in the legs, feeling of heaviness in the legs, paresthesia, edema, skin changes due to blood stagnation), varicose veins of the lower extremities (visible, permanent, segmental, vein dilatations, giving it a serpentine course), as well as symptomatic treatment of haemorrhoids. Chronic venous insufficiency (CVI) is a disease resulting from the dysfunction of the veins transporting blood from the lower parts of the body towards the heart, as a consequence of which some blood flows back, thus hindering the proper functioning of the veins.
Dobenox – contraindications to use
Dobenox should not be used in case of hypersensitivity to calcium dobesylate or any component of the preparation. The preparation should not be used in the first trimester of pregnancy and during breastfeeding.
Contraindications to use (or an indication to change the dosage of the preparation) may be: severe renal failure, chronically recurrent catarrhal gastritis, and gastric or duodenal ulcer disease.
Due to the fact that the preparation contains lactose, it is not recommended to use it for people suffering from rare hereditary galactose intolerance, primary lactase deficiency or malabsorption of glucose-galactose.
Dobenox – side effects
Dobenox may cause undesirable effects, although they do not have to occur in all patients using this preparation. Rarely, nausea, diarrhea, skin reactions, joint pain may occur. Agranulocytosis may very rarely occur, causing a severe reduction in the overall immunity of the body.
Dobenox Forte
Dobenox is also available in the Forte version. Dobenox Forte has the same composition and action, but 1 tablet contains a double dose of the substance – 500 mg of calcium dobesilate.
Name of the drug / preparation | Dobenox |
Manufacturer | The Pharmaceutical Production Company Hasco-Lek SA |
Form, dose, packaging | Coated tablets, 250 mg, 30 capsules |
Availability category | Over-the-counter drug |
The active substance | Calcium dobesylate |
Indication | Varicose veins, venous thrombosis, leg pain and night cramps, congestion, paraesthesia, edema |
Dosage | The drug should be used after meals. Unless otherwise prescribed by a doctor, adults usually take 2-4 tablets a day. In the case of Dobenox Forte, the dosage is 1-2 tablets a day. |
Contraindications to use | Hypersensitivity to calcium dobesate or any component of the preparation. The preparation should not be used in the first trimester of pregnancy and during breastfeeding. |
Warnings | Severe renal failure, chronic relapsing catarrhal gastritis, and gastric and / or duodenal ulcer disease. |
Side effects | Rarely, nausea, diarrhea, skin reactions, joint pain may occur. Agranulocytosis may very rarely occur, causing a severe reduction in the overall immunity of the body. |