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It is widely known that type 2 diabetes has a negative impact on the condition of the entire body, leading to further diseases. American scientists have found that the list of damage caused by diabetes also includes faster aging of the brain. Diabetics are also more likely to develop dementia.
- The diabetic organism is exposed to serious damage resulting from the disease
- In addition to eye disorders or kidney diseases, diabetics are also at risk of dementia
- The aging of the brain in diabetics is about 26 percent. faster than in healthy people
- More current information can be found on the Onet homepage.
Type 2 diabetes accelerates the aging process of the brain
Type 2 diabetes makes the brain age faster – this was the conclusion of scientists from Stony Brook University in New York, Massachusetts General Hospital and Harvard Medical School in Boston, who analyzed data collected in the British Biobank on 20. 314 people aged 50 to 80. In the study group, 1012 people suffered from type 2 diabetes, and 19 thousand suffered from type 302 diabetes. XNUMX people were healthy. Their results in tests for cognitive abilities and the results of brain neuroimaging studies were compared.
Additionally, a meta-analysis of more than 90 studies on brain aging in patients with type 2 diabetes and in people without diabetes was performed.
Diabetics have greater cognitive deficits
As the researchers observed, compared with the control group – matched in terms of age, sex, education and the presence of hypertension, type 2 diabetics had greater cognitive deficits, especially in terms of the so-called executive functions (including attention control, cognitive inhibition, inhibition control, working memory and cognitive flexibility) and the pace of information processing.
Moreover, a comparison of neuroimaging studies using magnetic resonance imaging (MRI) revealed that type 2 diabetes was associated with faster gray matter atrophy of the brain, especially in the ventral striatum (a structure important for executive functions, including behavioral control), the cerebellum and crust, and with changes in brain activity. Scientists estimated that the process of gray matter atrophy occurred in the brains of people with diabetes by approximately 26 percent. faster than the natural aging of the brain.
The negative impact of diabetes on the brain was greater the longer the disease lasted.
According to the lead author of Botond Antal’s work at Stony Brook University, the neurological changes associated with type 2 diabetes can occur long before the disease is diagnosed. “So when type 2 diabetes is diagnosed using conventional testing, patients may have permanent irreversible brain damage,” the researcher emphasizes.
Co-author Lilianne Mujica-Parodi from Stony Brook University points out that type 2 diabetes may accelerate brain aging, possibly due to energy deficiencies that alter brain structure and function.
“Our results support the need for research into biomarkers of type 2 diabetes in the brain and for treatments that specifically target its neurological effects,” concludes Mujica-Parodi. (PAP)
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