Contents
Dihydroxycholecalciferol (1,25 (OH) 2D3) is a hormone mainly produced by the kidneys. Its synthesis increases in the states of hypocalcemia and hypophosphatemia, and under the influence of calcitonin and parathyroid hormone. It plays an important role in the regulation of calcium and phosphate metabolism (it stimulates the processes of bone mineralization and the absorption of calcium and phosphate from the gastrointestinal tract, and is involved in the process of bone remodeling).
When do we perform the dihydroxycholecalciferol test?
Indications for the determination of dihydroxycholecalciferol:
1. Disorders of calcium and phosphate metabolism.
2. Rickets, osteomalacia, osteoporosis.
3. Suspicion of primary hyperparathyroidism.
4. Recurrent nephrolithiasis.
5. Suspected sarcoidosis.
Dihydroxycholecalciferol – the course of the study
1. Material for the study of dihydroxycholecalciferol: serum.
2. Preparation for the test: on an empty stomach (at least 8 hours).
3. The course of the study: one-time blood sampling from a vein in the arm.
4. Waiting time for the result of dihydroxycholecalciferol: 1 Day.
5. Norma: 50-150 pmol/l (20-60 pg/ml).
Comments: Dihydroxycholecalciferol belongs to the group of fat-soluble vitamins. In addition, it affects the nervous system, increases muscle strength, has an immunomodulatory effect and enhances antibacterial resistance.