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Adenoids are pathological overgrown tissues of the nasopharyngeal tonsil. The disease is most often diagnosed in children aged 3 to 7 years, although adults can sometimes get sick. With adenoids, there is difficulty in normal nasal breathing, night snoring, voice changes, rhinitis. The disease is dangerous for its complications, including: hearing loss, decreased general immunity, the formation of malocclusion, developmental delay, frequent infections, etc. Therefore, adenoids must be treated in a timely manner.
If you start therapy in the early stages of the development of the disease, then you can get by with conservative methods. When the adenoids are running, it will be impossible to avoid the operation. Dezrinit is a drug that is often prescribed for adenoids. It helps to relieve inflammation and eliminate the main symptoms of the disease.
General characteristics of the medicinal product
Dezrinit is a nasal spray, which is available in polyethylene bottles equipped with a dispenser. The main active ingredient is mometasone furoate monohydrate, a topical glucocorticosteroid. Also in the composition of the drug there are auxiliary components (polysorbate, citric acid monohydrate, etc.), but they do not have any effect on the course of the disease.
The liquid in the vial with the drug has a milky color, it is represented by a homogeneous suspension. Vials are available for purchase containing 60 and 140 doses.
The effect of Desrinite in adenoids
The medicinal properties of the drug Dezrinit are determined by its main active ingredient – mometasone.
The use of a nasal spray for adenoids allows you to achieve the following effects:
The drug fully blocks the cascade of the inflammatory response, blocking the production of inflammatory mediators (substances that the body itself synthesizes in order to fight infection).
Reducing tissue swelling, facilitating nasal breathing.
Prevention of further destruction of lymphoid tissue.
Reducing the size of adenoid vegetations, which often avoids surgery. Dezrinit is prescribed even for adenoids of the third degree.
Treatment of secretory otitis as a complication of adenoids.
Improving the aeration of the paranasal sinuses, spontaneous sanitation of the nasal cavity, unloading fistulas, which were previously blocked by overgrown adenoid tissue.
Relieve allergy symptoms.
The drug is prescribed for children who have undergone an adenotomy procedure, which avoids repeated operations.
After local administration of the drug, it is possible to create its maximum concentration in the nasopharyngeal cavity directly on the adenoids. Therefore, the effect comes quickly and lasts for a fairly long period of time.
How to use Dezrinit for the treatment of adenoids?
Before the first use of the drug, immediately after opening the vial, 10 “empty” clicks on the dispenser will be required. This must be done in order to establish a stereotyped dose spike. At one time, 100 mg of the drug (50 µg of mometasone) comes out of the dispenser. If the drug is used regularly, then re-“calibration” is not required. Provided that the bottle has been inactive for two weeks, it will be necessary to perform ten clicks again before using it.
Shake the vial vigorously before injecting the drug into the nasal cavity. Before irrigating the nasal cavity, it must be washed with a saline solution or other antiseptic. The cleaner the nasal passages, the more effective the treatment will be.
As for the dosage, its average values equate to two injections into each nasal passage once per knock. The doctor should select the dosage, since it can be changed, depending on the severity of the patient’s condition. If necessary, the frequency of use of the drug is increased up to two times a day.
For the treatment of children, you can try to start treatment with a single injection in each nostril, which is repeated 1 time per day. If there is no effect, then two injections are performed in each nostril. When it is possible to achieve control of the clinical picture, the dosage is again lowered.
You can expect the effect of using the drug Dezrinit already after 12 hours from the first application.
Important rules for using a drug bottle to avoid the development of atrophy of the nasal mucosa:
The bottle is inserted into the nostril strictly vertically.
Spray the drug into the right nostril with the left hand, and into the left nostril with the right hand.
Do not exceed the recommended number of injections.
The drug can be used for a long time. Sometimes it is prescribed for a period of 9 months to a year. This does not affect the effectiveness of the drug, and there is no tissue atrophy in the nasal passages. For the treatment of adenoids, it is advisable to use the drug in courses of 1-3 months, followed by a break of 1-2 months. Then the course of treatment can be repeated.
Possible harm
The use of Dezrinit is associated with a number of side effects, although in most cases the drug is well tolerated by patients.
The most common negative health effects are: headaches, nosebleeds, burning sensation in the nasal cavity, the formation of ulcers on the mucous membrane of the nasal passages.
Extremely rarely observed allergic reactions in the form of bronchospasm, shortness of breath, angioedema or anaphylactic shock. Rare side effects also include perforation of the nasal septum, irritation of the pharyngeal wall, distortion of smell and taste, increased intracranial pressure, cataracts or glaucoma.
When the drug should not be used
It is not recommended to prescribe the drug to mothers who are breastfeeding, as well as to pregnant women. Do not use Dezrinit to treat children under two years of age.
Other contraindications for use:
The presence of individual hypersensitivity to the components that make up Dezrinit.
Recent nose surgery.
“Fresh” trauma of the nose. The drug is not prescribed until the wound is completely healed.
The following conditions are not a contraindication, but the following conditions require special care when prescribing the drug: any respiratory tract infections, eye damage, prolonged and indolent inflammation of the nasal mucosa caused by bacterial, fungal or mixed pathogenic flora.
Important information
The systemic availability of the drug is less than 0,1%. This means that it practically does not enter the bloodstream and does not spread throughout the body. On this occasion, clinical studies were carried out, which made it possible to establish that in children who took Dezrinit therapy for a year, there were no violations in growth and development, the synthesis of corticosteroids by the adrenal glands did not change. In the blood, the drug is not determined by any available methods.
The mucous membrane of the nasal passages during the use of the drug does not undergo atrophic changes, despite long-term treatment with Dezrinit. However, the use of corticosteroids is always associated with the risk of tissue atrophy, so periodic examination by an otolaryngologist is a must.
If a patient develops a fungal infection during treatment, then he needs to abandon Dezrinit.
Against the background of treatment with Dezrinit, suppression of local immunity is observed. This requires special care on the part of the patient. He needs to minimize contact with infected people, as the chances of infection are greatly increased.
Both children and adults who receive nasal glucocorticosteroid therapy should be under medical supervision.
The drug can be used to treat adenoids in people suffering from bronchial asthma. Moreover, the improvement of nasal breathing in such patients contributes to the stabilization of their condition.
Dezrinit is unable to fight pathogenic flora. Therefore, if the disease is provoked not only by allergens, but also by viruses, bacteria or fungi, then treatment with specific drugs will be required.
An overdose of the drug is unlikely, since its bioavailability is extremely low. However, if a dose significantly exceeding the allowable dose has occurred, it is necessary to consult a doctor and spend some time under the supervision of specialists. No specific action should be taken.
It is not recommended to simultaneously combine the drug Dezrinit with other drugs from the group of glucocorticosteroids. This can lead to the fact that the function of the adrenal glands will be depressed.
It should be taken into account that the drug can not be stored for more than 2 months if it has been opened. When the integrity of the package is not broken, the shelf life of the medicinal product is 2 years.
Pros and cons of Dezrinit
Advantages of the drug Dezrinit:
The drug allows not only to eliminate the symptoms of adenoiditis, but also to treat the disease.
In some cases, the drug makes it possible to avoid surgical intervention aimed at removing the overgrown adenoid tissue.
The drug, unlike most other glucocorticosteroids, does not lead to atrophy of the mucous membrane of the nasal passages and sinuses.
The drug can be used for a long time.
The therapeutic effect comes quickly.
Cons of the drug Dezrinit:
The drug is released by prescription.
It can cause side effects.
The drug has contraindications.
The drug depresses local immunity, which increases the risk of contracting infectious diseases.
The drug has an age limit. It is not prescribed for children under two years of age, although adenoids are not often diagnosed at this age.
The drug does not have antiviral, antifungal or antibacterial activity.