Complete insufficiency of the pituitary gland
Syn.: Panhypopituitarismus.
Def .: Increased or complete impairment of the production of pituitary gland hormones.
Etiol .: Pituitary ischemia due to postpartum haemorrhage (Sheehan’s syndrome), primary tumors or pituitary metastases, Langerhans cell histiocytosis, syphilis, tuberculosis, sarcoidosis.
Clinical: Skin changes:
1. risk of severe sunburn – as a result of reduced melanin production due to lower ACTH and / or MSH levels;
2. pale skin – due to anemia and reduced skin blood flow;
3. dryness and swelling of the skin; smoothing facial skin folds, shallow wrinkles around the eyes and mouth;
4. generalized hair loss (primarily axillary hair), reduced facial hair intensity in men;
5. reduction in the size of the sebaceous and sweat glands; reducing sweat production;
6. thin and brittle nail plates, their growth is slowed down.
Heal: Hormonal.
Source: A. Kaszuba, Z. Adamski: “Dermatology. Practitioner Guide “; Czelej Publishing House