Ceroxim

Ceroxim is a systemic antibacterial agent. Beta-lactam antibiotic used to treat bacterial infections. It helps to treat conditions such as sinusitis, bronchitis and early stage Lyme disease, among others. The preparation is in the form of a powder for oral suspension and is available on prescription.

Ceroxim, Producent: Ranbaxy

Indications for taking Ceroxim

The indications of the preparation are the treatment of the following infections caused by bacteria susceptible to cefuroxime: upper respiratory tract infections – pharyngitis, laryngitis, tonsillitis, sinusitis, lower respiratory tract infections – acute bronchitis, exacerbation of chronic bronchitis, pneumonia, acute otitis media, urogenital infections – pyelonephritis , cystitis, urethritis, gonorrhea – acute uncomplicated urethritis and cervicitis, skin and soft tissue infections – e.g. furunculosis, pyoderma, impetigo, early stage Lyme disease and prevention of its late complications in adults and children after 12 years old.

Ceroxim and contraindications

A contraindication to the use of Ceroxim is hypersensitivity to any of its components or to cephalosporin antibiotics.

Dosage

Adults and adolescents from the age of 13:

1. Infections of the upper respiratory tract: 250 mg twice daily.
2. Exacerbation of chronic bronchitis or secondary infections of acute bronchitis: 250-500 mg twice a day.
3. Infections of the genitourinary system: 125-250 mg twice a day.
4. Infections of the skin and soft tissues: 250-500 mg twice a day.
5. Acute uncomplicated gonorrhea: single dose of 1 g.
6. Lyme disease in adults and children after the age of 12: 500 mg twice a day for 2 days.

In the case of treating pneumonia or exacerbation of chronic bronchitis, the doctor may use sequential therapy, in which he will first prescribe the intramuscular or intravenous administration of cefuroxime, and then the appropriate dosage of the preparation in the oral form.

Children who can swallow whole tablets:

1. Laryngitis, tonsillitis: 125 mg twice a day.
2. Acute otitis media: 250 mg twice daily.
3. In younger children, it is recommended to use the preparation in the form of an oral suspension (not in the form of tablets).

Children from 3 months of age – 12 years of age:

1. In most infections, the usual dose is 125 mg twice daily (or 2 mg / kg body weight daily in 20 divided doses), no more than 2 mg daily.
2. Acute otitis media in children from 3 months to 2 years of age: usually 125 mg twice a day (or 2 mg / kg body weight daily in 20 divided doses), no more than 2 mg a day;
3. Acute otitis media in children over 2 years of age: 250 mg twice a day (or 2 mg / kg body weight daily in 30 divided doses), no more than 2 mg a day.
4. There is no clinical experience with the use of the preparation in infants under 3 months of age.
5. In elderly patients, patients with impaired renal function and those undergoing dialysis, no special precautions are necessary, as long as the daily dose does not exceed 1 g.

Use:

Ceroxim should be taken orally. The preparation in the form of a powder for oral suspension should be taken with a meal and the preparation in the form of tablets 15-30 minutes after a meal. The tablets should be swallowed whole and not chewed, broken or crushed.

Ceroxim restrictions

1. Long-term use of antibiotics may cause overgrowth of resistant bacteria and fungi (mainly yeasts).
2. During the treatment of borreliosis, the so-called Jarisch-Herxheimer reaction (fever, headache, chills, increased heart rate, muscle pain, bone pain, itching, nausea, vomiting, skin rashes) which is usually self-limiting.
3. Before taking Ceroxim, consult your doctor and inform him if you have had a history of hypersensitivity reactions to cephalosporins, penicillins, or to other medications or allergens.
4. The safety and efficacy of the preparation in children under 3 months of age has not been established.
5. Ceroxim may impair the ability to drive motor vehicles and operate machinery.
6. Patients with hereditary problems associated with fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not use the preparation because it contains sucrose.
7. Caution should be exercised in women in the first trimester of pregnancy. Pregnant women may use the drug only if the doctor deems it necessary.
8. Nursing women should consult a doctor before taking the preparation.

Ceroxim and possible side effects

They may occur during the treatment with Ceroxim: Candida overgrowth, eosinophilia, headache, dizziness, diarrhea, nausea and abdominal pain, transient increases in liver enzymes. Positive Coombs test, thrombocytopenia, leukopenia, vomiting, skin rashes In addition, with an unknown frequency, the following may occur: overgrowth of Clostridium difficile, haemolytic anemia, drug fever, serum sickness, anaphylaxis, Jarish-Herxheimer reaction, pseudomembranous colitis , jaundice (mainly congestive), hepatitis, urticaria, pruritus, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.