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Ceftriaxone is a prescription antibiotic. It is produced in the form of vials, more precisely in the form of a powder for the preparation of a solution. The drug is administered intravenously or intramuscularly. The pack contains 10 vials. Ceftriaxone is not a refunded drug. What is the use of the drug? What is the correct dosage?
What exactly is Ceftriaxone? It is a β – lactam antibiotic, third generation cephalosporin. The drug is primarily bactericidal. The composition of the drug is designed to block the synthesis of the bacterial cell wall, which in turn leads to the complete elimination of bacteria. Bacteria that are not resistant to the substance of the drug include: S. agalactiae, S. aureus, green streptococci, S.pneumoniae, i.e. gram-positive aerobes. Gram-negative aerobic bacteria that are not resistant to the antibiotic include: N. gonorrhoea, N. meningitidis, H. parainfluenzae, B. burgdorferi, P. mirabilis. How does Ceftriaxone work? What should the dosage look like? Do special precautions need to be taken during the treatment?
Ceftriaxone – action
Ceftriaxone is an antibiotic recommended for use in cases of infection with ceftriaxone-sensitive bacteria. These types of conditions include bacterial endocarditis, acute otitis media, complicated urinary tract infections, nosocomial and post-hospital pneumonia, and complicated skin and soft tissue infections. The drug is also used in the treatment of people diagnosed with gonorrhea or syphilis.
Ceftriaxone is also recommended in the treatment of advanced or early stage of Lyme disease. The antibiotic is also often used in preoperative prophylaxis. Ceftriaxone is prescribed in neutropenic patients who develop fever most likely due to a bacterial infection.
Before starting antibiotic therapy, proper and complete tests are necessary to confirm or exclude infection with bacteria that are resistant to ceftriaxone, in such a situation it is necessary to implement combination therapy with other antibiotics.
It should be remembered that the use of probiotics is very important during therapy.
Ceftriaxone – contraindications
As with virtually any antibiotic therapy, side effects may occur. First of all, you cannot use the drug in people who are at risk of allergy to any component of the drug.
Adverse reactions to the use of the drug include:
- hypersensitivity reactions, for example anaphylactic shock, in which case immediate discontinuation of treatment is necessary.
- Studies have shown that the drug may displace bilirubin from protein connections, so the agent should not be used in premature babies or newborns born on time, but with jaundice, hypoalbuminemia, hyperbilirubinemia or acidosis.
- special care should be taken in people taking other solutions containing calcium, due to the possibility of precipitation.
- if anemia is detected in a patient during the treatment, treatment should be discontinued immediately.
- long-term use of the drug may lead to pseudomembranous colitis or colitis.
- Ceftriaxone can cause inflammation of the kidneys and liver.
- nephrolithiasis may be a side effect due to calcium precipitation in the kidneys.
Long-term treatment with the drug should be combined with regular, follow-up blood tests.
Before use, read the leaflet, which contains indications, contraindications, data on side effects and dosage as well as information on the use of the medicinal product, or consult your doctor or pharmacist, as each drug used improperly is a threat to your life or health.