Booster protects only three months? Protection against the Omicron is fading faster than previously thought
Start COVID-19 vaccine Frequently asked questions Where can I get vaccinated? Check if you can get vaccinated

The latest study shows that the level of neutralizing antibodies against the Omikron COVID-19 variant drops significantly around three months after the booster injection. It is possible that routine booster vaccinations will be needed in the long run, as will annual flu shots.

  1. Updated COVID-19 boosters may be available in the fall to provide better protection against the Omicron and its new sub-variants.
  2. For many people, it has been several months since the COVID-19 booster shot. Are those not yet eligible for the second booster still protected?
  3. This protection seems to be getting weaker, according to a new study conducted by the US Consortium of Clinical Research in Infectious Diseases of the National Institute of Allergy and Infectious Diseases.
  4. Omicron gains more and more immunity to vaccines over time.
  5. More current information can be found on the Onet homepage.

Omicron more and more resistant to vaccines. Their composition needs to be changed

According to the June study, most boosters, whether from Pfizer, Moderna or Johnson & Johnson, provide strong protection against Omicrons. In particular, they were supposed to cause high levels of neutralizing antibodies against an early Omikron strain called BA.1. However, in the three months following booster vaccination, antibody levels were reduced by 2,4 to 5,3-fold.

It’s not everything. The data also show that the later variants of the Omikron variant – the BA.2.12.1 and BA.4 / BA.5 variants – were 1,5 and 2,5 times less likely to be neutralized with the booster vaccine than BA.1, respectively. According to the authors of this discovery, Omikron is gaining more and more immunity to vaccines over time.

Last month, the US Food and Drug Administration (FDA) recommended that vaccine manufacturers develop modified boosters that contain the spike protein component Omikron BA.4 / BA.5 in addition to the current formulation of the vaccine. Pfizer-BioNTech and Moderna have already shared data on vaccine candidates with regulators. These should provide stronger protection against Omicron and older variants that may be active in the fall.

What does this mean for the COVID vaccination? Their schedule may resemble the seasonal flu shots

The United States may move to a vaccination schedule similar to the seasonal flu approach, according to verywellhealth.com.

The flu vaccine is prepared annually based on the strain expected to infect during the flu season.

However, COVID-19 is different in this regard as there is no fixed seasonal cycle that comes and goes over time. The emergence of new mutations and the large number of infections this summer, beyond the disease season, is evidence of this.

Influenza vaccine efficacy

It is important to know if we will still need regular doses of COVID-19 booster vaccines in the long run, and if so, whether annually will suffice.

Experts recall that COVID-19 vaccines save lives and prevent serious diseases, especially those who have immunodeficiency. The fact that boosters do not stop infection as expected does not change the fact that they are still effective in preventing death and serious disease.

The protection provided by vaccines is maintained, even though antibody levels decline several months after dosing. But careful research still needs to be done to determine how low levels are too low, and how this can vary from person to person.

The immune boost induced by a standard booster will provide protection and help our immune system respond faster to an Omicron infection. People eligible for a booster should take it and then see what the official guidelines will be in the fall for the “booster” vaccine.

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