It is used for skin disinfection before injection, blood collection, needle biopsy, infusion or transfusion, for aseptic wound care, treatment of bacterial and fungal infections, disinfection of skin and mucous membranes before surgical procedures.
Betadine – solution for application to the skin (Also)
| form, dose, packaging | availability category | the active substance |
| liquid 0,1 g / ml (10%) (30 ml, 1000 ml) | OTC (over-the-counter) | jodopowidon (povidone-iodine) |
ACTION
Iodophore with a bactericidal effect
INDICATIONS AND DOSAGE
Skin disinfection prior to injection, blood sampling, needle biopsy, infusion or transfusion. Apply to healthy, intact skin for 1-2 minutes.
Aseptic wound care, treatment of bacterial and fungal infections, disinfection of the skin and mucous membranes prior to surgery. Use a 10% solution.
Complete and partial disinfection of the patient before surgery (antiseptic bath). Spread 1% solution evenly on the patient’s body and leave it for at least 2 minutes, then rinse with lukewarm water.
Use undiluted or in 10% (1:10 dilution) and 1% (1: 100) solutions, depending on the application site. The solution should be diluted immediately before use.
CONTRAINDICATIONS
Hypersensitivity to iodine or any component of the preparation, thyroid dysfunction, hyperthyroidism, Duhring’s herpetic dermatitis, kidney failure. Do not use before and after treatment of hyperthyroidism with radioactive iodine.
WARNINGS
Preparation for topical application. Treatment should be discontinued if skin irritation or hypersensitivity reactions occur. The use of high doses of the preparation in young children should be avoided due to the greater sensitivity to iodine and the increased risk of hyperthyroidism. In newborns and infants up to 6 months of age, the preparation can be used only in the case of a precise diagnosis and absolute indications; thyroid function should be monitored. Protect children against the possibility of swallowing or taking the preparation into their mouths. Caution should be exercised in patients with a history of thyroid disease where high doses of iodine may cause hyperthyroidism; the application time should be limited to 14 days and the application area should be limited to no more than 10% of the body surface; monitoring of thyroid function in these patients and individual treatment is recommended. In patients with latent thyroid disorders, especially the elderly, long-term use of the preparation (more than 14 days) or on large areas of the skin (more than 10% of the body surface) is allowed only after consultation with a doctor; monitoring of these people for the early symptoms of hyperthyroidism is required (up to 3 months after the end of treatment) and, if necessary, thyroid function tests. Particular caution should be exercised in patients with renal insufficiency. Do not use regularly in patients currently treated with lithium. If symptoms of an overactive thyroid appear, thyroid function tests should be performed. The iodine contained in the preparation may affect the results of some diagnostic tests or make it impossible to perform them; Depending on the planned examination, there should be a sufficiently long interval (1-4 weeks) between the end of the treatment and the examinations. The preparation has oxidizing properties and may cause reversible discoloration of clothes (remove stains with warm water and soap or use an ammonia solution), corrosion of metals. Avoid contact of the preparation with the eyes; in case of irritation, rinse with water for 10-15 minutes and consult an ophthalmologist. Use in pregnant and breastfeeding women only after consulting a doctor and only if absolutely indicated for use. The dose and duration of treatment should be limited; the absorbed iodine can penetrate the placenta and also into the breast milk and cause disturbances in the development and function of the thyroid gland in the newborn.
INTERACTIONS
The preparation is antibacterial in the pH range from 2 to 7. Use with enzymatic ointments for wound healing, unsaturated organic compounds, proteins, antiseptics can mutually weaken the effect of the preparations. Due to the risk of interactions, do not use preparations containing mercury (risk of creating a corrosive chemical compound), silver, hydrogen peroxide, benzoic acid or taurolidine. The preparation has oxidizing properties and may affect the results of some laboratory tests (e.g. cause false positive results of tests for the presence of blood or glucose in the stool or urine). The use of the preparation may also make it difficult or impossible to perform thyroid scintigraphy, determination of protein-bound iodine, testing with radioactive iodine, and treatment of thyroid diseases with iodine. Do not use long-term or on large surfaces in patients currently treated with lithium. Do not use with reducing, acidic or alkaloids-containing preparations.
SIDE EFFECTS
The following may occur: renal dysfunction, acute renal failure, local skin reactions, hypersensitivity reactions (contact dermatitis, psoriasis-like lesions, redness, appearance of small blisters). Long-term use may cause hyperthyroidism, especially in patients with a history of thyroid disease.