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Stress, increased mental and physical stress, weakened immunity during an epidemic of infectious diseases contribute to the depletion of energy reserves. Metabolic drugs normalize metabolic processes in the body and are used in the treatment and prevention of many diseases.
Top 5 effective metabolic drugs according to KP
1. Corylip
Active active ingredients – carboxylase, riboflavin, thioctic acid. The agent has a metabolic effect. Corilip is available in the form of rectal suppositories. It is taken 2-3 suppositories per day for 10 days (for adults in stressful situations, mental or physical stress, to increase immunity). In more serious conditions, the dosage is adjusted by the doctor.
Carboxylase is an essential element for the synthesis of vitamin B1. Regulates the acid-base balance of the body.
Riboflavin is vitamin B2. Participates in the regulation of growth and reproductive functions of the body.
Thioctic acid (alpha-lipoic acid) is an antioxidant, hepatoprotector. Protects cells from exposure to exo- and endotoxins.
Effect on the body:
- regulates carbohydrate, fat, protein metabolism;
- protects the liver – hepatoprotective effect;
- increases the resistance of cells and tissues to conditions of lack of oxygen;
- regulates the acid-base balance in the body;
- improves the condition of the skin and mucous membranes;
- reduces the risk of complications during pregnancy.
Indications:
- increased mental and / or physical stress;
- to increase immunity during seasonal colds, before preventive vaccination;
- to prepare a woman’s body for pregnancy and childbirth;
- bacterial, viral infections (also acute intestinal infections);
- before and after the operation period.
Important! Contraindicated in case of allergy to the components of the drug, in inflammatory diseases or bleeding from the rectum. Allowed during pregnancy and children from 1 year. Children under 1 year of age are prescribed during an epidemic of infectious diseases, before routine vaccination, and also with insufficient weight gain. During lactation, you should refrain from taking the drug. Korilip is compatible with all drugs.
2. Cytoflavin
Active active ingredients – inosine, nicotinamide, riboflavin, succinic acid. Has a metabolic effect. The drug is available in the form of tablets. It is taken orally 2 tablets 2 times a day for a month.
Succinic acid is an organic acid that is produced by every cell in the body. Participates in cellular respiration.
Riboflavin is vitamin B2. Regulates growth processes in the body and plays an important role in reproductive processes.
Nicotinamide – vitamin PP. An essential element of protein and carbohydrate metabolism.
Inosine is involved in cellular respiration.
Effect on the body:
- stimulates tissue respiration;
- increases the resistance of cells and tissues to conditions of lack of oxygen;
- inhibits oxidation processes and the formation of free radicals;
- metabolic energy correction.
Indications:
- increased irritability, fatigue;
- prolonged mental and/or physical stress;
- consequences of a stroke;
- hypertensive encephalopathy;
- cerebral atherosclerosis.
Important! Contraindicated in case of hypersensitivity to the components of the drug, during pregnancy or lactation, in case of serious diseases of the gastrointestinal tract and / or kidneys, arterial hypertension, gout, children under 18 years of age. Simultaneous reception with antibacterial drugs, antidepressants only after consulting a doctor.
3. Idrinol
The active ingredient is meldonium. Has a metabolic effect. The drug is available in the form of hard gelatin capsules. It is taken orally 2 capsules a course of 10-14 days.
Meldonium is a metabolic agent that, under conditions of increased stress on the body, provides the necessary supply of oxygen to cells and the removal of toxic substances.
Effect on the body:
- provides the necessary supply of oxygen to the cells;
- prevents the accumulation of toxic products and protects body cells from damage;
- has a general tonic effect;
- ensures rapid recovery of energy reserves;
- improves physical endurance;
- mental performance improves.
Indications:
- decreased mental performance (used to improve memory and concentration);
- during physical overload.
Important! Contraindicated in case of hypersensitivity to the components of the drug, during pregnancy or lactation, with increased intracranial pressure, with serious diseases of the liver and kidneys, in children under 18 years of age.
4. Carnicetin
The active ingredient is acetylcarnitine. It has a neuroprotective, antioxidant, metabolic and stimulating energy metabolism effect. The drug is available in the form of hard gelatin capsules. It is taken orally for 6-12 capsules in a course of 1-4 months.
Acetyl-L-carnitine is a biologically active substance of natural origin. It is present in almost all organs and tissues of the body. It is an important element in the metabolism of carbohydrates and fatty acids.
Effect on the body:
- influence on lipid metabolism – the breakdown of fats;
- energy generation;
- protects brain tissue from ischemia (local reduction in blood flow);
- neuroprotective property;
- prevents premature aging of brain cells;
- anti-amnestic property (improves learning processes, memory);
- improves the regeneration processes even of nerve cells after injuries or endocrine damage.
Indications:
- decreased mental performance (used to improve memory and concentration);
- neuropathy (damage to the nerves of the peripheral nervous system);
- vascular encephalopathy;
- early stage of Alzheimer’s disease.
Important! Contraindicated in case of allergy to the components of the drug, during pregnancy or lactation, children under 18 years of age.
5. Dibikor
The active ingredient is taurine. Has a metabolic effect. The drug is available in the form of tablets. It is taken orally 500 mg 1 time per day for several months.
Taurine is an amino acid that contains sulfur. It is independently synthesized in the body and supplied with food.
Effect on the body:
- normalizes the exchange of potassium and calcium in cells;
- regulates oxidative processes;
- has antioxidant properties;
- improves metabolic processes in all tissues and organs;
- normalization of blood pressure.
Indications:
- diabetes mellitus type 1 and 2;
- cardiovascular failure;
- when taking antifungal drugs.
Important! Contraindicated in case of hypersensitivity to the components of the drug, during pregnancy or lactation, children under 18 years of age. Simultaneous reception with cardiac glycosides only after consulting a doctor.
How to choose a metabolic drug
Metabolic drugs are selected depending on the needs of the body. They differ in active substance and, as a result, in the mechanism of action. They also differ in the form of release: tablets, capsules, rectal suppositories. The most popular active substances are carboxylase, riboflavin, thioctic acid, taurine, acetylcarnitine and others. The selection of the drug is carried out by the doctor depending on the needs of the body.
The advantage of metabolic drugs is that they are practically incapable of provoking an overdose and some are allowed during pregnancy and are indicated for children under 1 year old.
Popular questions and answers
We discussed important issues related to metabolic drugs with therapist Tatyana Pomerantseva.
What are metabolic drugs?
Classification:
• anabolics (aimed at enhancing the processes of anabolism – increasing muscle mass, increasing strength and endurance);
• proteins and amino acids;
• vitamins and vitamin-like substances;
• lipid-lowering agents;
• correctors of bone and cartilage metabolism;
• macro and microelements;
• regulators of water and electrolyte metabolism;
• drugs that affect the exchange of uric acid;
• enzymes;
• other metabolites.
What are metabolic drugs used for?
Metabolism has two mandatory stages:
1. Anabolism is a process of plastic metabolism, in which more complex ones are formed from simple substances. During this, proteins, fatty acids, amino acids and other substances are synthesized.
2. Catabolism – the process of disintegration of complex substances into simple ones with the release of energy.
Violation in even one of the stages can lead to serious consequences. Effective metabolic drugs normalize processes and ensure the normal functioning of the body.
Appointed for:
• increased energy consumption of the body (stress, physical or mental strain);
• disorders of fat, protein or carbohydrate metabolism;
• violation of the metabolism of vitamins, micro or macro elements.
How are metabolic drugs different from vitamins?
Vitamins are prescribed for:
• replenishment of deficiency of biologically active substances;
• treatment of hypovitaminosis;
• are part of complex therapy in the treatment of acute or chronic diseases.
Vitamins can provoke an overdose. They are prescribed only on the recommendation of a doctor, taking into account the clinical picture, anamnesis, mandatory laboratory and instrumental studies.
Metabolic drugs are prescribed only for the correction of metabolic processes. An overdose of these funds is almost impossible.
Sources:
- Register of Medicinal Products of Russia® RLS®, 2000-2021.
- J. Tepperman, H. Tepperman Physiology of Metabolism and the Endocrine System, 1989
- D. Sychev, L. Dolzhenkova, V. Prozorova Clinical pharmacology. General issues of clinical pharmacology, 2013.