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Measurement of the batroxobin (reptylase) time is one of the methods of blood clotting testing. The principle of the test is similar to the determination of thrombin time, but the test uses the enzyme reptylase, not thrombin. What is batroxobin time and when is it marked? What are the standards?
Batroxobin time – what is it?
The function of batroxobin time used in the diagnosis of coagulation problems is similar to that of thrombin time (TT). This means that it is applicable in analyzing the time taken to initiate a clot formation. The process of converting fibrinogen into insoluble fibrin is considered here.
While the TT test requires the use of thrombin to activate clotting, an enzyme isolated from snake venom is used in determining the batroxobin time. It is a reptilase or ankrod, hence the alternative test names – reptile time and ancode time. The effectiveness of these enzymes is due to their activity similar to thrombin, but there is also a positive difference – their measurement is not interfered by immunological antithrombin, heparin or hirudin.
Batroxobin time – indications
The main indication for the determination of batroxobin time is the coagulation test in patients treated with heparin and antithrombins. If such a specific situation does not exist, as a rule, a thrombin time study is planned. On the basis of the batroxobin time result, it is possible to identify the cause of prolonged bleeding, to detect coagulation problems occurring in renal failure and diseases of the liver parenchyma, as well as fibrinogen dysfunctions (also congenital).
- Read more about clotting: Prothrombin time, or how fast blood clots
Batroxobin time – the course of the study
Measurement of batroxobin time it is similar to the TT test and is based on the analysis of venous blood. As a rule, you should go to the examination in the morning with a referral from the attending physician. Before that, you should also consult the question of taking medications on the day of taking and the days preceding them.
Batroxobin Time is a test also known as Reptylase Time and Accroding Time.
- Material for the test of epoxide time: citrate plasma.
- Preparation for the test of epoxide time: The test is performed on an empty stomach, therefore the patient should eat the last meal the day before, at least 8 hours before collection. It is recommended to rest and calm down 15 minutes before donating blood, but rest is recommended. Before the test, you should give up physical activity, and vigorous exercise is not recommended for two or three days. If you are taking solid medications or other pharmacological agents, be sure to inform your doctor about it before the examination.
- The course of the RT examination: The patient gets a referral from the doctor and sits down at the designated place. A single blood sample is taken from a vein in the arm with a sterile syringe. The injection site is then pressed with a sterile gauze to stop blood flow and minimize the risk of bruising. The blood is sent to the laboratory, where it is added to non-reptylase or bankrod, and the time of fibrinogen transition to fibrin is measured.
- Waiting time for test results: up to two days.
- Batroxobin (Reptylase) Time Norm: 16 to 22 seconds.
Batroxobin time – deviations from the norm
Batroxobin time should not exceed the upper limit of the norm, as such an indicator means that the coagulation process is prolonged. The reason for this may be the improper structure of fibrinogenemia, its deficiency (hypofibrinogenemia) or its lack (afibrinogenemia). Abnormal RT result is also observed in the syndrome of disseminated intravascular coagulation, liver cirrhosis, kidney diseases and multiple myeloma.
Do you need interpretation of test results? Are you worried about your symptoms? Contact your doctor. Make an online teleconsultation with your family doctor at haloDoctor.pl to get answers to your questions.
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