Bad blood results

What can poor globulin levels mean?

I had a blood test recently and I wanted to ask if I have a globulin level of 18,9 at a norm of 23,0-35,0 and a total bilirubin of 22,71 at a norm of 0,17-17,10 should I worry? I would like to add that I have been feeling very bad lately, I am constantly tired and I have no appetite ~ Karolina

It is best to start the diagnosis of non-specific ailments with a visit to the doctor and a medical examination, not with random biochemical tests. It should be remembered that by definition 2,5% of healthy people will have a result above the norm and the same number below the norm. Your globulin and bilirubin levels are slightly abnormal and are probably irrelevant.

Globulins are present in several fractions: alpha-globulin, beta-globulin, gamma-globulin. The decreased alpha and beta globulin levels are not of established clinical significance. Reduced levels of gamma-globulins occur in various diseases where their production is reduced or their loss through the gastrointestinal tract is increased. In order to determine which globulins are missing, a proteinogram is performed. Increased bilirubin levels (hyperbilirubinemia) may be caused by various diseases of the liver (including acute and chronic hepatitis), bile duct diseases (e.g. cholelithiasis), blood, and may be caused by the administration of certain medications. Slight hyperbilirubinemia in asymptomatic patients is often caused by the so-called Gilbert’s disease – a congenital dysfunction of bilirubin excretion from the body of no clinical significance. Please report the results to the doctor, and he will determine the further procedure after examining you.

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