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Azycin is a macrolide antibiotic used to treat bacterial infections. It is intended for general use. The antibiotic is in the form of film-coated tablets, but is also available in the form of granules for oral suspension. The active ingredient of Azycin is azithromycin. When is it advisable to use Azycin? How to take an antibiotic and what side effects to watch out for?
Azycine – properties
The action of Azycin is based on its active substance, which is azithromycin – an antibiotic from the macrolide group, which is a semi-synthetic derivative of erythromycin and devoid of some of its disadvantages. Effectively inhibits bacterial ribosomes, co prevents the growth and multiplication of bacterial cells. It is well absorbed and quickly penetrates from the serum into the tissues. Thanks to its accumulation in phagocytes, the distribution of the drug to inflammatory tissues increases, which has a positive effect on the shorter treatment process.
- Check also other drugs that contain azithromycin
Azycine – application
Azycin is used to fight infections caused by microorganisms sensitive to azithromycin. They include:
- otitis media
- sexually transmitted diseases (uncomplicated non-gonococcal chlamydial urethritis)
- uncomplicated skin and soft tissue infections (secondary pyoderma, erysipelas, impetigo, erythema migrans, acne vulgaris vulgaris).
In case of contraindications to the use of penicillin, Azycin can be used to treat upper respiratory tract infections: sinusitis, streptococcal pharyngitis and / or tonsillitis. The antibiotic is also given to patients with acute bronchitis or exacerbations of chronic bronchitis, as well as in mild to moderately severe pneumonia (including interstitial pneumonia).
See: Antibiotics – types, action, use and side effects
Azycine – contraindications
You cannot use Azycine if you are allergic to any of the ingredients of the drug. The exact composition is described in the package leaflet. If in doubt, consult your doctor or pharmacist. Azycin should not be administered to people with severe liver disease. It should not be used as an outpatient severe pneumonia. It is prohibited to use in parallel with ergot derivatives – it can lead to poisoning.
It is not advisable to use Azycin during pregnancy or breastfeeding. The exceptions are when the doctor considers that the benefits of using the drug outweigh the potential risk to the child.
Azycine – precautions
People who want to prescribe Azycin should first consult with him about ailments and health conditions such as:
- predisposition to develop cardiac arrhythmias (e.g. bradycardia, ever-occurring arrhythmias, severe heart failure, too low or too high potassium or magnesium levels, but also disturbances in the levels of other electrolytes);
- severe liver or kidney problems;
- symptoms of superinfection, as well as burn wound infections.
In some cases, Azycine may cause dizziness and convulsions, which may adversely affect the ability to drive vehicles and operate machinery and equipment. When used for non-gonococcal urethritis, it may delay or mask the symptoms of gonorrhea or syphilis.
If you develop new bacterial or fungal infections (e.g. yeast infections) while using Azycin, or develop diarrhea during or after treatment, consult your doctor immediately. Caution should be exercised when administering Azycin to patients with neurological or mental disorders.
Azycine – dosage
For adults and children weighing more than 45 kg, the dosage depends on the specific disease:
- infections of the respiratory tract, skin and soft tissues – 500 mg once daily for 1 days or administer a dose of 1500 mg for 5 days according to the schedule: on the first day – dose of 500 mg, and on the next four days – 250 mg;
- migratory erythema – 1 g in the first day, then 500 mg once a day,
- sexually transmitted diseases – one time 1 g.
In children weighing less than 45 kg, the use of Azycin oral suspension is not recommended. It is also acceptable to administer the drug in 125 mg coated tablets.
Taking more than the recommended dose may cause symptoms similar to those of the correct dose, such as diarrhea, severe nausea, vomiting or temporary hearing loss. In case of overdose of Azycine ask your doctor or pharmacist for advice. It is also recommended to use activated charcoal and, if necessary, symptomatic treatment or other necessary medical assistance.
Azycine – side effects
Some people taking Azycin may experience side effects from the drug. Diarrhea occurs very often, abdominal pain, nausea and vomiting are also often observed, as well as a change in some blood test results – an increase in leukocytes and a decrease in the level of bicarbonate.
Among side effects occurring uncommonly and rarely you can mention, among others angioedema, anorexia, insomnia, palpitations, hot flushes, candidiasis, fungal and bacterial infections, gastroenteritis, dysuria, myalgia, rashes, agitation, liver disorders and others. A complete list of possible ailments that can potentially arise after taking this antibiotic is provided in the product information leaflet.
Certain side effects of Azycin require immediate discontinuation of the antibiotic and contact your doctor. This applies to allergic reactions (swelling, trouble breathing, rash), severe skin reactions (e.g. Stevens-Johnson syndrome, erythema multiforme), severe diarrhea (especially if there is blood and mucus in the stools) or uterine haemorrhage.
Azycine – price
The number of tablets in the package determines the price for the drug. For example, for 6 tablets of Azycin 250 mg, we will pay approximately PLN 17-23, for 6 tablets of 500 mg approximately PLN 19-22, while the cost of a package containing 12 tablets of 500 mg of azithromycin may exceed PLN 50. The prices given are indicative, they may change and vary depending on the place of purchase.
| Name of the drug / preparation | Azycine |
| Wstęp | Macrolide antibiotic used to treat bacterial infections. |
| Manufacturer | Polfa Pabianice SA |
| Form, dose, packaging | 250/500 mg, 3/6/12 mg film-coated tablets. |
| Availability category | Prescription drug. |
| The active substance | Azithromycin |
| Indication | Treatment of infections caused by microorganisms sensitive to azithromycin. |
| Dosage | – infections of the respiratory tract, skin and soft tissues: 500 mg once a day for 1 days, – migratory erythema: 3 g on the first day, then 1 mg once a day, – sexually transmitted diseases: 500 g once, |
| Contraindications to use | – allergic to any of the ingredients of the drug, – severe liver disease, – severe pneumonia, – during pregnancy or breastfeeding. |
| Warnings | Affecting the ability to drive vehicles and operate machinery and equipment. |
| Interactions | When used in the presence of ergot derivatives, it can lead to poisoning. |
| Side effects | – may delay or mask the symptoms of gonorrhea or syphilis, – diarrhea. |
| Other (if any) | x |
Read also:
- The antibiotics stop working. What is antibiotic resistance?
- What should you eat while taking an antibiotic and after finishing the treatment?
- Do antibiotics fight the coronavirus?
Before use, read the leaflet, which contains indications, contraindications, data on side effects and dosage as well as information on the use of the medicinal product, or consult your doctor or pharmacist, as each drug used improperly is a threat to your life or health. Do you need a medical consultation or an e-prescription? Go to halodoctor.pl, where you will get online help – quickly, safely and without leaving your home.