Contents
In line with its mission, the Editorial Board of MedTvoiLokony makes every effort to provide reliable medical content supported by the latest scientific knowledge. The additional flag “Checked Content” indicates that the article has been reviewed by or written directly by a physician. This two-step verification: a medical journalist and a doctor allows us to provide the highest quality content in line with current medical knowledge.
Our commitment in this area has been appreciated, among others, by by the Association of Journalists for Health, which awarded the Editorial Board of MedTvoiLokony with the honorary title of the Great Educator.
Aviomarin is a drug designed to combat nausea and vomiting. It is especially recommended during motion sickness. Moreover, Aviomarin prevents nausea and vomiting and helps to get rid of these ailments. Check what is worth knowing about Aviomarin.
Aviomarin – action
The active substance of Aviomarin is dimenhydrinate, which is an anti-emetic, antihistamine and cholinolytic drug. It works by reducing the action of histamine and blocking the muscarinic acetylcholine receptors. Aviomarin has an antiemetic and anti-nausea effect, therefore it is perfect for motion sickness.
Aviomarin is a drug that crosses the blood-brain barrier and strongly inhibits the vomiting center in the medulla and labyrinthine reflexes. Moreover, the antiemetic properties enhance the anticholinergic properties. Aviomarin relieves smooth muscle tension, gastrointestinal motility and salivation.
The active substance of Aviomarin is absorbed quickly after oral administration, and the effect of the drug is felt after 30 minutes. The effect lasts up to 6 hours. Aviomarin is metabolised in the liver and entirely eliminated via the kidneys within 24 hours of a single dose.
Check it out: Drugs behind the wheel – what effect do different drugs have on the driver?
Aviomarin – indications
Aviomarin is given for:
- the prevention of motion sickness;
- prevention and treatment of nausea and vomiting – however, remember that Aviomarin will not help against nausea and vomiting caused by drugs administered during chemotherapy.
Aviomarin – contraindications
The main contraindication to the use of Aviomarin is hypersensitive, i.e. allergic to any ingredient of the drug or other antihistamines. In addition, contraindications are:
- asthma attacks;
- angle-closure glaucoma;
- porphyria;
- epilepsy;
- pheochromocytoma;
- prostatic hyperplasia and the associated residual urine in the bladder.
Moreover, Aviomarin should not be given to children under 6 years of age.
Check it out: Labyrinth – what functions does it perform? Labyrinth disorders and methods of their treatment
Aviomarin – precautions
It should be remembered that even if there are indications for the administration of a given preparation, it may not always be used. Certain diseases and other health-related conditions may constitute contraindications to the use of Aviomarin or are an indication for a dosage change. In certain situations, it is also necessary to undergo regular checkups.
Special caution when using Aviomarin people should keep:
- with impaired liver function;
- with hyperthyroidism;
- with bradycardia, that is, a reduced heart rate;
- with low levels of potassium (hypokalaemia) and magnesium in the blood (hypomagnesaemia);
- with chronic respiratory disorders, asthma;
- with a narrowed pylorus;
- with congenital prolongation of the QT interval on the ECG or other cardiac disorders, such as cardiovascular disease, ischemic heart disease, or heart problems;
- are taking medicines that cause QT prolongation on the ECG or medicines that cause hypokalaemia, i.e. low blood potassium levels.
It should also be remembered that Aviomarin significantly affects the ability to drive and use machines or devices. The drug reduces psychomotor performance, therefore people driving vehicles or operating machines and devices should not take Aviomarin.
Check it out: How do antiemetics work?
Aviomarin – dosage
Aviomarin is available in the form of oral tablets. They should be taken about 30 minutes before a planned trip or administration of a drug to which we react badly. The tablet should be washed down with water. Aviomarin can be taken with or without food. However, it should be remembered not to exceed the recommended doses, because it will not affect the effectiveness of the drug, and may adversely affect our health and even life. Any doubts related to the use of Aviomarin and its safety should be consulted with a doctor.
The dosage of Aviomarin is as follows:
- adults and adolescents over 14 years of chewing – administered 50-100 mg in one dose, which can be rubbed every 4-6 hours. However, it should be remembered not to exceed the daily dose of 400 mg of the substance;
- children aged 6-14 years – a single dose of 50 mg repeated if necessary every 6-8 hours. At the same time, remember not to exceed the daily dose of 5 mg / kg of the child’s body weight per day and the daily dose of 150 mg.
Aviomarin can be given to children who can swallow a tablet on their own. Also note that due to the high the content of the active substance Aviomarin not intended for children under 6 years of age.
Check it out: Kinetosis, or motion sickness – check what is worth knowing about it?
Aviomarin – pregnancy and breastfeeding
Pregnant and breastfeeding women should remember never to take any medication without consulting a doctor. At this particular time, it is very important to clarify all doubts about the risks and benefits of using it with your doctor before taking any preparation. Consultation is also recommended for women planning or trying to conceive.
Aviomarin is not a drug recommended in the third trimester of pregnancy. Moreover, the use of the drug in the first and second trimesters is allowed only when the physician deems it absolutely necessary, which means that in his opinion the expected benefits are higher than the possible risks associated with the administration of the drug. Remember that this is what the doctor evaluates the risk of administering Aviomarin during this period of pregnancy.
The active substance of Aviomarin, i.e. dimenhydrinate, passes into breast milk. This means that breastfeeding women should not use Aviomarin, unless the doctor considers it necessary and decides that the benefits of using the medicine outweigh the possible risks. Most often, the doctor recommends taking certain precautions and performing regular check-ups in such a situation.
Check it out: How can I deal with motion sickness?
Aviomarin – interactions
Before starting to use Aviomarin, inform your doctor about all medications you have recently taken, including those without a prescription. In addition, while taking the drug, you should not drink alcohol, as it may increase the effect. Aviomarin may interact with:
- drugs that inhibit the central nervous system, i.e. sleeping pills, sedatives, barbiturates, narcotic painkillers or muscle relaxants. These drugs may increase depression of the central nervous system;
- anticholinergics – Aviomarin may increase their effect (these are atropines, tricyclic antidepressants);
- MAO inhibitors – Aviomarin used in parallel increases the cholinolytic effect of the preparation;
- diazepam – Aviomarin works synergistically with it. Diazepam is antagonistic to amphetamine and its derivatives;
- corticosteroids and oral anticoagulants – Aviomarin reduces their effect;
- with bismuth salts and painkillers, psychotropic drugs and scopolamine – this can lead to visual impairment;
- drugs that prolong the QT interval on the ECG, such as class IA or III antiarrhythmics, antibiotics such as erythromycin, neuroleptics, antihistamines, and drugs causing hypokalemia – caution is advised;
- with ototoxic antibiotics, i.e. those that damage hearing, e.g. streptomycin, viomycin, kanamycin – Aviomarin used simultaneously may mask the symptoms of hearing impairment caused by the antibiotic.
In addition, Aviomarin should be discontinued 3 days before scheduled allergy testing, as the drug may falsify the results.
Aviomarin – side effects
Aviomarin, like all medicines, may cause side effects. However, it should be remembered that side effects do not occur in every person taking Aviomarin. In addition, the benefits of taking it most often outweigh the inconvenience of side effects. The following side effects after administration of Aviomarin include:
- somnolence;
- dizziness;
- concentration disorders;
- blurred vision;
- increased intraocular pressure;
- nausea;
- vomiting;
- constipation;
- diarrhea;
- stomach pain;
- dry mouth;
- difficulties urinating;
- muscle weakness;
- fatigue or agitation;
- sleep disturbance;
- anxiety;
- tremors;
- arterial hypotension;
- headaches;
- insomnia;
- skin allergic reactions;
- skin hypersensitivity to light;
- liver disorders;
- cholestatic jaundice;
- hemolytic anemia;
- exfoliative dermatitis;
- decreased appetite.
Before use, read the leaflet, which contains indications, contraindications, data on side effects and dosage as well as information on the use of the medicinal product, or consult your doctor or pharmacist, as each drug used improperly is a threat to your life or health. Do you need a medical consultation or an e-prescription? Go to halodoctor.pl, where you will get online help – quickly, safely and without leaving your home. Now you can use e-consultation also free of charge under the National Health Fund.