Syn.: Primary cutaneous anaplastic large cell lymphoma – C-ALCL.
Def .: Large-cell lymphoma of pleomorphic T cells with CD30 + antigen primary cutaneous or primary nodal.
Epid .: It concerns adults.
Clinical: A single red tumor or a dozen or so tumors or infiltrates without disintegration or with ulceration, sometimes the tumors resolve spontaneously.
Hist .: Pleomorphic / anaplastic tumor tissue, large cells with horseshoe-shaped nuclei, sometimes multinuclear cells similar to Reed-Sternberg cells.
DL: Hist.-Pat.
DI: CD30 + marker in tumors, loss of pan-T marker in tumor cells.
DR: Primary cutaneous lymphomas type B.
Year: Good 5-year survival of approx. 80%.
Heal: X-rays.
Lit.: [1] Liu H.L., Hoppe R.T., Kohler S. i wsp.: CD30 cutaneous limfoproliferative disorders: the Stanford experience in lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma. J Am Acad Dermatol 2003, 49; 1049-58.
Source: A. Kaszuba, Z. Adamski: “Lexicon of dermatology”; XNUMXst edition, Czelej Publishing House