Acenol – how quickly relieves pain? Composition, dosage, precautions

The drug is used for pain of various origins.

Acenal (Galena)

form, dose, packaging availability category the active substance
tabl. 0,3 g (20 tabl.) OTC (over-the-counter) paracetamol (paracetamol)

ACTION

Non-opioid drug with analgesic and antipyretic properties.

INDICATIONS AND DOSAGE

Pains of various origins (head, teeth, muscles, joints, menstrual pains), fever. Orally; adults. 0,3–1 g every 4 h; max. 4 g / d; do not administer more often than 5 times a day. Kids. 8. – 10. 0,4 g every 4-6 h; 10. – 12. 0,48 g every 4-6 h.

CONTRAINDICATIONS

Hypersensitivity to any component of the preparation. Severe renal and hepatic dysfunction, hypertension, anemia.

WARNINGS

Paracetamol tablets should not be given to children under 8 years of age. Even after obtaining the expected therapeutic effect (such as the disappearance of pain or a decrease in fever), the drug should not be used for more than 3 days without consulting a doctor. It is especially urgent to contact your doctor if the pain or fever intensifies or does not disappear despite the use of the preparation. To avoid overdosage, check that other concomitant medications do not contain paracetamol. Use of the drug during pregnancy and breastfeeding only after consulting a doctor and only if absolutely necessary

INTERACTIONS

Acetylsalicylic acid (aspirin) and diflunizal increase the concentration of paracetamol in the plasma. Hepatotoxicity may be increased by simultaneous administration of paracetamol with metyrapone and probenecid, zidovudine, isoniazid and antibiotics from the rifamycin group. Phenytoin, phenobarbital and sulfinpyrazole increase the metabolism of paracetamol. Caution should be exercised when using non-steroidal anti-inflammatory drugs (NSAIDs) with paracetamol. Paracetamol administered with MAO inhibitors may cause agitation and high fever. Metoclopramide accelerates the absorption of paracetamol.

SIDE EFFECTS

The following side effects may occur: haemolysis occurring occasionally in people with blood cell enzymopathy, glucose-6-phosphate dehydrogenase deficiency (mainly in Mediterranean and black populations); hypothermia (body temperature below 35,5 ° C) (previously only reported in children); impaired kidney and / or liver function, liver damage (mainly in alcoholics or during long-term use). Extremely rare: rash and hypersensitivity (only a few cases have been reported) with typical symptoms of shock onset. Isolated cases of haematological disorders, i.e. thrombocytopenia and agranulocytosis.

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