5 best analogues of Euthyrox
Euthyrox is a drug for hormone replacement therapy, which is included in the list of vital medicines. We will find out from the expert if Eutirox has analogues, how they work and whether they can become an equivalent replacement for the original drug

Euthyrox contains only one active ingredient – levothyroxine sodium. This is a synthetic analogue of the thyroid hormone, which, when ingested, begins to perform the functions of a natural hormone.1. The goal of treatment with Euthyrox is to maintain the level of thyroid hormones at a physiological level so that the person feels healthy.

Euthyrox is prescribed for people with hypothyroidism, diffuse toxic goiter, euthyroid goiter, as well as patients who have completely or partially removed the thyroid gland1. Treatment of almost all forms of hypothyroidism requires the constant use of Euthyrox or its analogues. Under medical supervision, Eutiroks can be taken by pregnant and lactating women.

The standard dosage regimen is half an hour before meals or 3-4 hours after. Do not take Eutiroks together with other medicines, you need to maintain an interval of at least 15 minutes. If we are talking about iron and calcium preparations or antacids, such as Maalox and Almagel, then the interval should be 4 hours.

The effect of the use of Euthyrox develops 7-12 days after the start of treatment. In case of discontinuation of the drug, its effect persists for a similar period of time.

The manufacturer – the German company MERCK – produces Eutiroks in tablets with different contents of levothyroxine sodium: 25, 50, 75, 88, 100, 112, 125, 137 and 150 mcg.

Euthyrox should not be used:

  • with hypersensitivity to the components of the drug;
  • in acute myocardial infarction and acute myocarditis;
  • people with untreated adrenal insufficiency and untreated thyrotoxicosis1.

People with arrhythmia, diabetes mellitus and coronary heart disease should take the drug with caution and under medical supervision.1. It should be borne in mind that Euthyrox contains lactose, so it is less digestible in people with lactase deficiency.

Rating of the top 5 inexpensive and effective analogues of Euthyrox according to KP

Together with an expert, we have compiled a list of the 5 best Euthyrox analogues that can be purchased at the pharmacy chain. The rating includes medicines from Russian and foreign manufacturers. Our list includes Euthyrox analogues based on levothyroxine sodium, as well as Euthyrox substitutes that contain other active ingredients.

Euthyrox and its analogues are prescription drugs that are taken only on prescription. Therefore, our rating is for informational purposes and cannot be a guide to buying.

1. L-thyroxine Berlin-Chemie

Perhaps today it is the most popular analogue of Euthyrox. L-thyroxine from Berlin-Chemie is available in tablets of 50, 75, 100, 125 and 150 mcg2.

The main difference between this drug and Euthyrox and its analogues is the absence of lactose in the composition.2. L-thyroxine from Berlin-Chemie uses calcium phosphate as an auxiliary substance, so the drug is suitable for people with lactase deficiency7. Indications and contraindications for L-thyroxine are the same as for Euthyrox.

full analogue of Euthyrox according to the active substance; does not contain lactose; many dosage options.
sometimes not available in the pharmacy network.

2. L-thyroxine

Another Russian drug on the list of Euthyrox analogues. The OZON company produces L-thyroxine in tablets containing 50 or 100 micrograms of levothyroxine sodium3. The drug is prescribed for hypothyroidism, euthyroid goiter, after partial or complete removal of the thyroid gland.3. Contraindications for the drug are the same as for other thyroid hormones.

like Euthyrox, contains levothyroxine sodium; easy to find for sale.
There are few dosage options – 50 and 100 mcg.

3. Bagothyrox

Bagothyrox is available in tablets containing 50, 100, and 150 micrograms of levothyroxine sodium.4. As excipients, lactose and dyes are used, which make it possible to distinguish tablets with different dosages from each other.4. As for indications and contraindications, they are identical to Euthyrox.

a complete analogue of Euthyrox, since it contains only sodium levothyroxine.
only 3 dosage options; dyes are present in the composition; rarely on sale.

4. Novotiral

This is the only substitute for Euthyrox in the ranking. It contains not one, but two synthetic thyroid hormones – 100 micrograms of levothyroxine sodium and 20 micrograms of liothyronine sodium5. Novotiral is prescribed for hypothyroidism of various origins5.

The drug can not be used for thyrotoxicosis, severe disorders in the work of the adrenal glands and the cardiovascular system5. The price of Novotiral is much higher than that of Euthyrox analogues.

an effective combined preparation of a well-known manufacturer.
is not an analogue of Euthyrox; costs much more than the original drug.

5. L-thyroxine Reneval

The Russian analogue of Euthyrox is available in tablets containing 25, 50 and 100 mg of levothyroxine sodium.6. The tablets have a special mark – risk, so it is convenient to divide them in half.

Like Euthyrox, L-thyroxine compensates for the deficiency of thyroid hormones in hypothyroidism and after thyroid surgery.6. Contraindications are standard for all synthetic thyroid hormones – this is untreated hyperthyroidism (excess thyroid hormones), hypersensitivity to components, acute myocardial infarction and acute myocarditis, adrenal insufficiency6.

a complete analogue of Euthyrox.
rarely happens in the pharmacy network; There are 3 dosing options.

How to choose an analogue of Euthyrox

“For the first time, levothyroxine was synthesized in 1927 by British chemists,” says geriatrician Gleb Krasnov. – Over the past 90-odd years, various pharmaceutical companies have learned how to produce levothyroxine. Therefore, the choice should be based on the following points:

  • price;
  • availability;
  • tolerability (no side effects).

The patient should be aware that all Euthyrox analogues act in almost the same way and can serve as an equivalent substitute for each other. The exception is Euthyrox substitutes, for example, the same Novotiral mentioned in the rating, which has a different pharmacological activity.

Combined drugs can be taken instead of Euthyrox only as prescribed by a doctor and it is imperative to monitor your well-being: regularly measure your pulse and blood pressure, take blood tests to check the level of thyroid stimulating hormones.

Reviews of doctors about the analogues of Eutiroks

– Sometimes doctors say that they prefer L-thyroxine from Berlin-Chemie. But, most likely, this is due to the work of medical representatives who actively advertise the German drug. The formula of the active substance – levothyroxine sodium – is the same for all analogues of Euthyrox. The different reaction of patients to analogues is explained by differences in the composition of excipients and production technology, – notes geriatrician Gleb Krasnov.

Popular questions and answers

Euthyrox is a popular drug for the treatment of hypothyroidism. Recently, due to increased demand for drugs, the drug has disappeared from pharmacies, forcing patients to look for a replacement. Gleb Krasnov, a geriatrician, answers the most frequent questions about Euthyrox analogues.

When can Euthyrox analogues be used?

– Indications for taking Euthyrox analogs: hypothyroidism, euthyroid goiter, thyroid surgery. But in any case, the drug and dosage should be selected by the doctor.

What happens if you stop taking Eutiroks and switch to an analogue?

– Theoretically, the transition to the analogue of Euthyrox in the same dosage does not cause any consequences. But when changing the drug in the patient’s body, an excess or deficiency of thyroxine may occur, therefore, in this case, doctors recommend taking tests for the level of TSH (thyroid-stimulating hormone) every 2 months7.

After switching to an analogue, I recommend that you monitor your reactions and feelings and choose the drug that you are most comfortable using. If one causes nausea or dizziness, switch to another. Usually practitioners tend to ignore or pay little attention to side effects, although this is a very important aspect. Take the drug that causes the fewest side effects. And levothyroxine works the same for everyone, in any preparations.

Sources of:

  1. Vidal. Reference book of medicines. Euthyrox. https://www.vidal.ru/drugs/euthyrox__32016
  2. Vidal. Reference book of medicines. L-thyroxin Berlin-Chemie https://www.vidal.ru/drugs/l-thyroxin_75_berlin-chemie__17851
  3. Vidal. Reference book of medicines. L-thyroxine OZONE. https://www.vidal.ru/drugs/l-thyroxin__23557
  4. Vidal. Reference book of medicines. Bagothyrox. https://www.vidal.ru/drugs/bagothyrox__6665
  5. Vidal. Reference book of medicines. Novotiral. https://www.vidal.ru/drugs/novothyral__598
  6. Vidal. Reference book of medicines. L-Thyroxine Reneval. https://www.vidal.ru/drugs/l-thyroxin-reneval
  7. The problem of interchangeability of drugs L-thyroxine. “Effective pharmacotherapy. Endocrinology”. Demidova M. A. https://umedp.ru/articles/problema_vzaimozamenyaemosti_preparatov_ltiroksina.html

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