In herbal medicine, standardized extracts of butterbur rhizome (Petasites officinalis) to prevent and treat migraine attacks. Two clinical trials published in the early 2000s demonstrated the effectiveness of this herbaceous plant in preventing migraine. In the oldest study¹, daily intake of standardized butterbur extracts (Petadolex®) for 3 months significantly reduced the frequency of migraine attacks. The second try² clearly confirmed the results of the first, participants who took 150 mg of butterbur extract every day for 4 months saw a sharp drop in migraine attacks. 

Dosage : People more prone to migraine attacks can take between 50 mg and 75 mg of standardized extract of butterbur with a meal, twice a day for 2 to 4 months. 

Sources : Sources : Grossman W, Schmidramsl H. An extract of Petasites hybridus is effective in the prophylaxis of migraine. 2001 Jun; 6(3):303-10. Lipton RB, Göbel H, Einhäupl KM, Wilks K, Mauskop A. Petasites hybridus root (butterbur) is an effective preventive treatment for migraine. 2004 Dec 28; 63(12):2240-4.