10 best Wobenzym analogues
Wobenzym is used in the treatment of many diseases – from SARS and influenza to diseases of the heart and blood vessels, respiratory organs, skin, etc. The drug is not always on sale, so the search for its analogues worries many. Together with an expert, we select Wobenzym substitutes and tell you how they work

Wobenzym is a drug with anti-inflammatory and immunomodulatory effects.1. It contains enzymes (enzymes) – protein substances of plant and animal origin1. Once in the bloodstream, they suppress inflammation and increase the body’s defenses. The manufacturer claims that Wobenzym has antibacterial and antiviral activity, reduces blood viscosity, improves lipid metabolism, strengthens the walls of blood vessels1.

Wobenzym is available in the form of enteric coated tablets. The drug is considered safe and suitable for long-term use – the course of treatment can range from 2 weeks to several months.

List of top 10 inexpensive and effective Wobenzym analogues according to KP

Only Phlogenzym can be attributed to direct analogues of Wobenzym. This is a drug with a similar composition from the same manufacturer – the German company MUCOS EMULSIONS. Therefore, our rating contains the most substitutes for Wobenzym – drugs and dietary supplements with other active ingredients, but with a similar effect.

1. Phloenzyme

This is the best analogue of Wobenzym with a very similar composition. The active components of Phlogenzym are plant and animal enzymes bromelain, rutin and trypsin.2. The drug is available in the form of tablets that have anti-inflammatory, immunomodulatory, blood-thinning and anti-edematous effects.2.

Flobenzym is prescribed in the recovery period after injuries and operations, with diseases of the veins and arteries, cardiovascular pathologies, hepatitis, acute and chronic diseases of the genitourinary tract.

Contraindications: age up to 18 years, individual intolerance to the components, blood clotting disorders.

composition and action similar to Wobenzym.
high price in the segment; not always on sale.
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2. Bronchomunal

An immunostimulant that is widely used to treat infectious diseases of the upper respiratory tract, including chronic bronchitis3. The drug helps fight a bacterial infection, which often complicates the course of the disease.3. Bronchomunal is available in capsules, which are taken once a day. The duration of treatment is determined by the doctor.

You can not take Bronchomunal with hypersensitivity to the components, children under 6 months old, as well as pregnant and lactating women.

can be used to treat children older than 6 months; convenient regimen – 1 time per day.
may cause diarrhea, abdominal pain, cough, shortness of breath.
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3. Immunal

Immunomodulator of plant origin based on Echinacea purpurea extract. Stimulates the body’s defenses and has an anti-inflammatory effect4. It is used for infectious and inflammatory diseases of the respiratory and urinary tract, for the prevention of acute respiratory viral infections and influenza, with long-term antibiotic therapy4. Immunal is available as a solution for oral administration, the dosage and regimen are prescribed by the attending physician.

The drug is not prescribed for children under 12 years of age, pregnant and lactating women, people with progressive systemic and autoimmune diseases (tuberculosis, systemic lupus erythematosus), blood diseases and a tendency to allergies.

preparation of plant origin, contains a complex of biologically active substances.
a large number of contraindications and side effects.
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4. Echinacea tincture

Herbal immunomodulator based on the herb Echinacea purpurea. It increases the nonspecific immune defense of the body and is used in the complex therapy of infectious diseases of the respiratory and urinary tract, with long-term antibiotic treatment, for the prevention of influenza and SARS.5. The tincture is taken orally. The dosage and duration of therapy is determined by the doctor.

Echinacea tincture should not be taken by women during pregnancy and lactation, people with a tendency to allergies, blood diseases, autoimmune pathologies and immunodeficiency states, as well as individual intolerance.

considered an effective immunostimulant.
many contraindications and side effects; specific taste.
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5. Immunorix

Immunomodulator with the active ingredient pidotimod, which activates cellular immunity6. Imunorix is ​​used in the complex therapy of infectious and inflammatory diseases of the respiratory tract and urinary system.6. The use of the drug allows you to speed up recovery, reduce the frequency of exacerbations and the risk of complications6. Imunorix can be used in parallel with antibacterial drugs.

The drug comes in the form of an oral solution, which is convenient for people who don’t like pills.

Contraindications: fructose intolerance, children under 3 years of age, hypersensitivity to pidotimod.

minimum contraindications and side effects.
Not everyone likes the method of application in the form of a solution.

6. Methyluracil

Methyluracil improves metabolism in cells and tissues, has an immunostimulating and anti-inflammatory effect.7. The drug is prescribed for pancreatitis, gastric and duodenal ulcers, radiation sickness, leukopenia against the background of the use of chemotherapeutic drugs7. Methyluracil also helps speed up tissue healing after burns, fractures, and other injuries.7. The drug is available in tablets, dispensed from pharmacies by prescription.

Do not take Methyluracil during pregnancy and lactation, with leukemia, lymphogranulomatosis, hemoblastosis, with hypersensitivity to the components and under the age of 3 years.

effectively restores damaged tissues, accelerates healing; can be used to treat children older than 3 years.
sometimes causes dizziness, which can interfere with the management of transport and complex mechanisms.

7. Immunophytol

Immunomodulator based on aloe juice and ascorbic acid8. It is produced in the form of a syrup, which is taken orally 2-3 times a day for two weeks or according to the scheme prescribed by the attending physician.

The drug activates the body’s immune system and helps with viral and bacterial infections of the respiratory tract8. Immunophytol is used in the complex therapy of sinusitis, pharyngitis, rhinitis and tonsillitis in adults and children over 3 years of age.8.

The drug is contraindicated in pregnancy, lactation, hypersensitivity to the components, while taking drugs that suppress the immune system.

a small number of contraindications; rare side effects; can be used to treat children older than 3 years.
Not everyone likes the taste of syrup.
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8. Sodium nucleinate

The active component of the preparation sodium nucleinate stimulates natural immunity and accelerates the processes of tissue regeneration9. Sodium nucleinate is prescribed for people with chronic viral and bacterial infections, chronic nonspecific lung diseases, immunodeficiency states9.

The drug is available in tablets that need to be taken 3-4 times a day.9. The course of treatment can range from 10 days to 6 weeks, depending on the severity of the disease.

Contraindications: hypersensitivity to the components of the drug, pregnancy and breastfeeding.

the minimum number of contraindications and side effects.
sometimes causes allergic reactions; not a very convenient regimen – tablets should be taken several times a day.

9. Ergoferon

Antiviral agent and immunomodulator with anti-inflammatory action10. Activates the body’s defenses and helps fight acute intestinal infections, influenza and SARS10. Produced in the form of tablets for resorption and solution for oral administration.

Contraindications: children under 6 months of age, individual hypersensitivity to the components, lactase deficiency, lactose intolerance.

there are practically no contraindications and side effects; different forms of release – in the form of tablets and solution.
in rare cases, it can cause an allergic reaction.
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10. Cycloferon

An antiviral and immunomodulatory drug is prescribed for the prevention and treatment of influenza, SARS and herpesvirus infections.11. The drug is effective against a wide range of viruses – the causative agents of most respiratory diseases11. It comes in the form of tablets to be taken once a day.

Cycloferon should not be taken by people with individual intolerance and with cirrhosis of the liver, as well as by pregnant and lactating women and children under 4 years of age. Take the drug with caution in acute gastrointestinal diseases and allergic reactions.

accelerates recovery and helps prevent the development of complications from influenza and other respiratory viral infections; convenient regimen – 1 time per day.
skin allergic reactions are possible.
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How to choose an analogue of Wobenzym

– The composition of Wobenzym is patented and is produced only under this trade name, so it will not work to find complete analogues – says pulmonologist Svetlana Bozhko. – The only option with similar active ingredients is Phlogenzym, but it is produced by the same pharmaceutical company and is not currently supplied to Russia. Therefore, we can only talk about Wobenzym substitutes, and here it all depends on the indications and contraindications, which are individual for each person. Therefore, it is better to entrust the choice of a substitute to the doctor.

Reviews of doctors about analogues of Wobenzym

“Since the drug does not have a clear evidence base, many doctors have long abandoned its use and switched to more effective medicines,” our expert notes. – When selecting drugs, specialists take into account the type and clinical course of the disease in a particular patient. To relieve pain in the joints, NSAIDs are used, for infectious diseases – antimicrobial and antiviral drugs, with a critical decrease in immunity – immunomodulators, etc.

Popular questions and answers

Svetlana Bozhko, a pulmonologist, answers the most common questions regarding Wobenzym analogues.

When can Wobenzym analogues be used?

– Most Wobenzym substitutes are immunomodulators that are recommended for the prevention and treatment of various infectious diseases. The expediency of prescribing one or another substitute should be discussed with the attending physician.

What happens if you stop taking Wobenzym and switch to an analogue?

– As I said, the effectiveness of Wobenzym has not been clinically proven. Therefore, most likely, there will be no negative consequences. And it is quite possible that the analogue chosen by the doctor will be more effective.

Although the disappearance of the drug from pharmacies caused a wide resonance, I do not see this as a serious problem. Wobenzym was used only as part of complex or alternative therapy, so it can always be replaced with other drugs that help to cope with the disease.

Sources of:

  1. Vidal. Reference book of medicines. Wobenzym. https://www.vidal.ru/drugs/wobenzym
  2. Register of medicines of Russia. Phlogenzym. https://www.rlsnet.ru/tn_index_id_6592.htm
  3. Vidal. Reference book of medicines. Bronchomunal. https://www.vidal.ru/drugs/broncho-munal__6805
  4. Vidal. Reference book of medicines. Immunal. https://www.vidal.ru/drugs/immunal__6874
  5. Vidal. Reference book of medicines. Echinacea tincture. https://www.vidal.ru/drugs/echinacae-galenopharm__18592
  6. Register of medicines of Russia. Imunorix. https://www.rlsnet.ru/tn_index_id_39468.htm
  7. Vidal. Reference book of medicines. Methyluracil. https://www.vidal.ru/drugs/methyluracil-5
  8. Vidal. Reference book of medicines. Immunophytol. https://www.vidal.ru/drugs/immunophytol
  9. Vidal. Reference book of medicines. Sodium nucleinate. https://www.vidal.ru/drugs/sodium_nucleinate__3693
  10. Register of medicines of Russia. Ergoferon. https://www.rlsnet.ru/tn_index_id_46844.htm
  11. Vidal. Reference book of medicines. Cycloferon. https://www.vidal.ru/drugs/cycloferon__3791

1 Comment

  1. Wobenzym ir Pflogenzym daro stebūklus visam organizmui. Jokio šalutinio poveikio.Todėl nutraukė jų tiekimą, kad žmonės pirktų cheminius vaistus, kuriuos vartojant nieko gero. Jokių analogų jiems nėra, reikia grąžnti juos į rinką ir taškas.

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