10 best drugs for hot flashes with menopause

Contents

Rating of the top 10 inexpensive and effective drugs for hot flashes with menopause according to the KP
How to choose drugs for hot flashes with menopause
Doctor’s comments
Popular questions and answers

Hot flashes during menopause are familiar to many women. Feeling hot, sweating, palpitations – such attacks last from 1 to 3 minutes and are repeated up to 10 times a day, and sometimes more often. Hot flush medications for menopause, which we selected together with experts, will help get rid of discomfort

Hot flashes during menopause are a consequence of a deficiency of estrogen hormones, which occurs in a woman’s body due to a decrease in ovarian function¹. Therefore, many effective drugs for hot flashes work as substitutes and make up for the lack of female sex hormones.¹. These are estrogen products that are used as part of menopausal hormone therapy.¹. As an alternative, non-hormonal agents can be used: phytoestrogens, herbal and synthetic drugs with a calming and antidepressant effect.².

Rating of the top 10 inexpensive and effective drugs for hot flashes with menopause according to the KP

Together with an expert, we have selected 10 effective drugs for hot flashes with menopause. The rating includes tablets, gels, patches and sprays. However, we do not advertise drugs and do not recommend self-medication. Any remedy from our rating can be taken only as directed by a doctor.

1. Prohynova

Dragee with a dosage of 2 mg contains an analogue of estrogen estradiol. The active ingredient compensates for the lack of estrogen in the female body. Due to the action of the drug:

hot flashes, tachycardia and sweating decrease or disappear;
irritability and depression disappear;
the elasticity of the skin and mucous membranes is maintained;
bones stop losing calcium.

Contraindications: breast cancer, existing or suspected estrogen-dependent oncological diseases, venous thrombosis and thromboembolism and a tendency to these conditions, acute and severe liver diseases, endometrial hyperplasia.

efficiency; complex action, since in addition to hot flashes, the drug helps to get rid of other symptoms of menopause; affordable price in the segment.

a wide range of contraindications.

2. Divigel

Contains synthetic estradiol – an analogue of the female sex hormone. With regular use, the drug helps to eliminate the symptoms of estrogen deficiency: hot flashes, sweating, mood swings, heart palpitations. Divigel also prevents the leaching of calcium from bone tissue and the development of osteoporosis, which often affects women during menopause.

Contraindications for Divigel are the same as for other estrogen-containing drugs: breast cancer, estrogen-dependent tumors (diagnosed or suspected), endometrial hyperplasia, vaginal bleeding of unknown origin, thrombosis and thrombophlebitis.

does not affect the gastrointestinal tract, since the active substance immediately enters the bloodstream; affordable price.

many contraindications; not a very convenient way to use it.

3. Klimara plaster

The drug looks like a transparent patch, inside of which there is a film with the active substance – estradiol, a synthetic analogue of the female sex hormone. The plasters are packaged in 4 bags and packed in a cardboard box. The patch is removed from the package and immediately pasted onto clean, dry skin. Applications are changed every 7 days. During this time, the active substance continuously penetrates the skin, which allows you to maintain a stable level of estradiol.

Contraindications are standard for estrogen-containing drugs: breast tumors and other tumors dependent on sex hormones, as well as thrombosis, thrombophlebitis and vaginal bleeding of unknown origin.

does not create a load on the liver and gastrointestinal tract, the active substance immediately enters the bloodstream; provides a stable concentration of estradiol in the body.

difficult to find on sale; not everyone is comfortable wearing a patch, besides, it can peel off under the influence of water.

4. Climactoplan

Non-hormonal homeopathic preparation contains components of natural origin and a small amount of excipients. Helps to reduce or completely stop symptoms such as hot flashes, nervous irritability, headaches.

Contraindications: hypersensitivity to components.

herbal preparation; the minimum number of contraindications; affordable price.

sometimes causes allergies; at the beginning of treatment, a temporary deterioration in the condition is possible.

5. Depression

Non-hormonal herbal preparation contains St. John’s wort extract. Available in the form of tablets (Deprim) and capsules (Deprim Forte). It has a mild antidepressant and calming effect, and also helps to normalize the digestive tract and increase the overall tone of the body.⁴. The drug helps to cope with increased irritability, anxiety, sleep disorders and hot flashes.⁴.

Contraindications: individual intolerance to the components, simultaneous use of MAO inhibitors.

efficiency; natural composition; minimum contraindications.

with prolonged use, it can cause a feeling of bitterness in the mouth; hard to find for sale.

6. Menoril plus

The dietary supplement contains resveratrol and genistein, plant-derived substances with an estrogen-like effect. They help to reduce or completely eliminate the unpleasant symptoms of menopause: hot flashes, sweating, headaches, dizziness, irritability. Vitamins K1 and D3 promote the absorption of calcium and reduce the likelihood of developing osteoporosis.

Contraindications: individual intolerance to the components of the drug.

natural composition; minimum contraindications.

the effect is not immediately noticeable.

7. Feminaspray

Dietary supplement in the form of a spray to be sprayed into the mouth. Contains vitamins E and D and resveratrol, a powerful natural antioxidant³. Resveratrol at low concentrations helps relieve menopausal symptoms, including hot flashes and excessive sweating.³. Feminaspray is intended for course use, but can also be used as an emergency remedy, for example, in situations where a woman feels the approach of a tide and wants to avoid it.

Contraindications: individual intolerance to the components.

natural composition; ease of use.

can cause allergies; not available in all pharmacies.

8. Estrophem

Produced in the form of dragees with a dosage of 2 mg, contains estradiol. The drug eliminates the symptoms of estrogen deficiency, including hot flashes, sweating, headache, decreased bone density. It is intended for course intake of 1 tablet per day. The duration of therapy is determined by the doctor.

Contraindications: breast cancer, diagnosed or suspected estrogen-dependent oncological diseases, vaginal bleeding of unknown origin, thrombosis, thrombophlebitis, endometrial hyperplasia, acute liver disease.

compensates for the lack of estrogen, reduces or completely eliminates the symptoms of menopause.

high price; quite a few contraindications; not combined with a number of drugs, including tranquilizers, anticonvulsants, some antibiotics.

9. Estrogel

Colorless transparent gel for external use. 1 g of estrogel contains 600 mg of estradiol. The active substance helps to eliminate the symptoms of menopause: hot flashes, night sweats, vaginal dryness, increased irritability. Estradiol also lowers blood cholesterol levels and helps prevent osteoporosis. The gel is applied to the skin 1 time per day daily or according to the scheme prescribed by the doctor.

Contraindications: estrogen-dependent tumors, breast cancer, thrombosis, thromboembolism, untreated endometrial hyperplasia, vaginal bleeding of unknown origin.

efficiency; does not affect the gastrointestinal tract, unlike drugs for oral administration.

not very convenient application – the gel must be applied to the skin and wait for complete absorption.

10. Klimadinon

A non-hormonal herbal preparation is available in the form of tablets and drops for oral administration. The active substance is an extract of the rhizome of cymifuge racemose. Climadinon has an estrogen-like and sedative effect and helps reduce menopausal symptoms, including hot flashes, irritability, and sleep disturbances.

Contraindications: hypersensitivity to ingredients, lactase deficiency, lactose intolerance.

preparation with herbal ingredients; affordable price; efficiency.

can cause skin allergic reactions, disorders in the liver and gastrointestinal tract.

How to choose drugs for hot flashes with menopause

Hot flashes should be prescribed by a doctor. First of all, this concerns estrogen-containing hormone replacement therapy drugs (Proginova, Estrazhel, Divigel and the like).

The standard drug selection scheme looks like this:

a woman comes to the doctor’s office and complains of hot flashes;
the doctor prescribes examinations: blood tests, ultrasound of the small pelvis and mammary glands, screening for cervical cancer;
with pronounced symptoms of menopause and the absence of contraindications, hormonal preparations are prescribed;
if estrogen replacement therapy is contraindicated, or a woman is against taking hormonal drugs, as well as with minor symptoms of menopause, phytoestrogens or drugs from other pharmacological groups are prescribed.

If a woman has started taking hormonal drugs, the next visit to the doctor should take place after 3 months. The doctor will again prescribe examinations to evaluate the effectiveness of therapy and identify possible side effects. After 6 months, another visit is needed to check, check the results, adjust the dose or change the drug, if necessary. After that, you need to visit a doctor at least once a year for a preventive examination.

Doctor’s comments

Most doctors agree that hot flashes and other menopause symptoms can and should be managed to improve a woman’s quality of life. Only the approach to therapy differs. Some doctors consider hormonal drugs to be the best drugs for hot flashes during menopause. Others prefer phytoestrogens, herbal antidepressants, and selective serotonin reuptake inhibitors (SSRIs) such as venflaxine, fluoxetine, sertraline². As a rule, treatment begins with non-hormonal drugs and only if indicated, they switch to menopausal hormone therapy.