10 best analogues of Nimesil
When we experience pain, the first thing that comes to our mind is the thought of pain medication. Nimesil, without a doubt, is one of the most effective drugs. However, the increased price and sales restrictions force us to pay attention to analogues.

Nimesil belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). The active ingredient in Nimesil is nimesulide.1. Unlike many similar drugs, nimesulide acts “pointwise” in the focus of inflammation and has a maximum analgesic effect. The main indications of the drug are associated precisely with this feature:

  • removal of acute pain (in the back, lower back, muscles, toothache);
  • pain with sprains and dislocations;
  • treatment of pain syndrome after injuries, operations, with arthrosis and other diseases of the joints;
  • primary dysmenorrhea (menstrual pain)1;

The reverse side of the effectiveness is a large number of contraindications. These include:

  • hypersensitivity to the components of the drug;
  • hypersensitivity to acetylsalicylic acid and other NSAIDs;
  • simultaneous use with other NSAIDs;
  • chronic inflammatory processes of the intestine in the acute stage;
  • exacerbation of peptic ulcer of the stomach and duodenum;
  • bleeding and perforation of the gastrointestinal tract in history;
  • severe forms of blood clotting disorders, heart and kidney failure;
  • liver disease;
  • fever with SARS and other infectious and inflammatory diseases;
  • pregnancy and lactation;
  • children’s age up to 12 years.

When taking the drug, side effects may occur in the form of nausea, vomiting, diarrhea, itching and skin rash, shortness of breath, swelling, increased blood pressure.

The drug from an Italian manufacturer is available in the form of granules for preparing a solution. It should be taken orally, dissolved in 100 ml of water, 1-2 times a day after meals.

Nimesil analogues also contain nimesulide and are produced by various pharmaceutical companies.

List of top 10 inexpensive and effective analogues of Nimesil according to KP

Together with our expert pharmacist Ksenia Veselova, we have compiled the top 10 effective analogues of Nimesil.

1. Nemulex

Nemulex is produced by a joint venture between Romania and Russia. The main active ingredient is nimesulide. Indications, contraindications and side effects are the same as for Nimesil. Nemulex has anti-inflammatory, antipyretic and analgesic effects2. The maximum concentration in the blood is reached after 1,5-2,5 hours.

Taking the drug is contraindicated in many conditions (the same as Nimesil), Nemulex should not be taken at elevated body temperature, against the background of symptoms of acute respiratory viral infections, during pregnancy, lactation and children under 12 years of age.

Application: 1 sachet (previously dissolved in water) 2 times a day after meals, but not more than 15 days.

effective pain reliever; fast action.
can not be used for ARVI and children under 12 years of age.

2. Naysulid

The preparation of a Russian manufacturer based on nimesulide. Naisulid also belongs to a new generation of non-steroidal anti-inflammatory drugs and has the same 3 actions: anti-inflammatory, analgesic and antipyretic. The drug is absorbed from the gastrointestinal tract and reaches its maximum concentration in the blood after 2-3 hours. It is prescribed for rheumatoid arthritis, joint pain with gout, arthritis, spondylitis, osteochondrosis, various pains in muscles, ligaments, tendons, joints, toothache and headache.

Naisulid is available in 3 dosage forms: conventional tablets and lozenges, as well as granules for solution preparation. Contraindications for use are the same as for Nimesil.

Application: the drug is taken 1 tablet (or sachet) twice a day after meals, but not more than 15 days.

effective, has various forms of release, there are lozenges.
May cause nausea, diarrhea, abdominal pain.

3. Resulid

Resulid is an Indian drug based on nimesulide. Available in the form of tablets and granules for the preparation of a solution (Resulid Fast). Resulid is prescribed for pain of various origins, has the same contraindications as Nimesil3.

According to the manufacturer, Resulid often causes gastrointestinal side effects: diarrhea, nausea, vomiting.

Application: 1 tablet or sachet 2 times a day after meals.

good analgesic effect, available in granules and tablets, affordable price.
often not available in retail stores.

4. Friend

Another fairly well-known Russian-made drug from the NVPS group, which contains nimesulide. Nise is available in the form of tablets, granules for solution, gel and spray for external use. The drug has a strong analgesic effect, helps with a variety of pains.

Indications, contraindications and side effects for Nise are the same as for Nimesil.

Application: 1 tablet 2 times a day after meals.

well-known brand, fast action, there are dosage forms for external use.
may cause drowsiness, dizziness and visual disturbances, which must be taken into account when driving vehicles and complex mechanisms.

5. Nimulid

Indian anesthetic drug Nimulid is produced most often in the form of lozenges. Also, the drug is available in the form of conventional tablets, suspensions, as well as a gel for external use. All dosage forms contain nimesulide as the main active ingredient. The lozenge dissolves very quickly in the mouth and does not require drinking water. The analgesic effect comes on fairly quickly and lasts for several hours.

Indications, contraindications and side effects are the same as for previous drugs. 

Application: put the tablet on the tongue and hold until completely dissolved, take 1 tablet twice a day after meals.

available in the form of conventional tablets, gel and suspension, quick effect, affordable price.
possible side effects from the gastrointestinal tract.

6. Aponil

Another analogue of Nimesil from a Cypriot manufacturer, which contains nimesulide. Aponil is available as conventional enteric-coated tablets. The maximum concentration of the drug in the blood occurs after 1-2 hours, and the therapeutic effect lasts up to 6-8 hours4.

 A special plus is that the drug has somewhat fewer contraindications. For example, unlike previous remedies, Aponil is also used for fever of various origins, including acute respiratory viral infections and other infections. The manufacturer warns that the drug may cause side effects from the gastrointestinal tract in the form of nausea, heartburn, stomach pain and diarrhea.4.

Application: twice a day, 1 tablet after meals.

can be used for fever (including ARVI);
not sold in all pharmacies.

7. Nimika

Nimik’s mouth-resolving tablets from an Indian company are a good alternative to Nimesil. The main active ingredient is nimesulide. The lower (compared to Nimesil) effectiveness of the drug is compensated by the low price and a much smaller set of contraindications: erosive and ulcerative diseases of the gastrointestinal tract in the acute phase, liver and kidney failure, 3rd trimester of pregnancy, lactation period, children under 12 years of age.

In addition to tablets, the drug is available in the form of a suspension, which is approved for use by children from two years of age. In addition to pain, the drug is also prescribed for fever of infectious and inflammatory origin.

Application: 1 tablet after meals 2 times a day.

can be used in children from 2 years in the form of a suspension, used for fever.
when taken simultaneously, it reduces the effectiveness of certain drugs: diuretics, anticoagulants, drugs to lower blood pressure.

8. Nimesan

The Indian drug Nimesan, like Nimesil, contains nimesulide. Like all other analogues, the drug has similar indications, contraindications and side effects. The main difference between Nimesan is its lower efficiency in the treatment of pain, therefore it is not suitable for severe pain.

The drug can only be used by people over 12 years of age, while it should be borne in mind that Nimesan cannot be taken simultaneously with other NSAIDs.

Application: 1 tablet 2 times a day after meals.

affordable price.
not suitable for severe pain, only one dosage form – tablets.

9. Prolid

And again, an Indian drug based on nimesulide, which is available in the form of lozenges. Prolide quite effectively copes with various types of pain, including muscle, headache and toothache.5, while being affordable (especially if you immediately purchase a large package of 100 tablets).

Prolide can be used for fever caused by inflammation of the upper respiratory tract5. The manufacturer does not indicate other differences in indications, contraindications and side effects from the original drug.

Application: 1 tablet twice a day after meals.

low price, copes with different types of pain.
Not everyone likes the taste of pills.

10. Nimesulide

The last on our list was a drug with the same name according to the active substance. Nimesulide is produced by a large number of companies, including in Russia, in the form of tablets, granules for suspension and gel for external use.6.

Indications for the use of Nimesulide – treatment of acute pain of various origins. Contraindications and side effects are typical for drugs in this group.

Application: 1 tablet twice a day after meals.

low price, large assortment, always in stock, there are various dosage forms.
inferior to Nimesil in terms of efficiency.

How to choose an analogue of Nimesil

Preparations based on nimesulide are very similar in the list of indications, and also have almost the same contraindications and side effects. The main differences are in the effectiveness of the drug and its price. In addition, some analogues have in their line not only granules for preparing a solution, but also classic tablets, lozenges, gels and sprays for external use. Some manufacturers produce suspensions that can be used by children.

It is important to remember that only a doctor should choose an analogue. All of these drugs have a large list of contraindications, so only a qualified specialist can evaluate all the pros and cons of a drug.

Reviews of doctors about analogues Nimesil

Non-steroidal anti-inflammatory drugs, which include Nimesil and its analogues, are symptomatic drugs. Therefore, replacing Nimesil with its analogue will not affect the treatment process in any way.

At the same time, most doctors note that it is Nimesil that most effectively copes with pain, so switching to an analogue is only advisable if there is intolerance to the components of Nimesil, or if you need to buy a cheaper drug.

Popular questions and answers

The most popular questions about Nimesil’s analogues are answered pharmacist Ksenia Veselova.

When can Nimesil analogues be used?

– The use of Nimesil analogue is possible at any stage of treatment. Here it must be borne in mind that many analogues are inferior to the original drug in terms of the effectiveness of the analgesic effect. Therefore, if you do not suffer from very severe pain, then you can easily get by with an analogue. The main thing is to first consult with your doctor and carefully study the contraindications to the use of a particular drug. 

What will happen if you stop taking Nimesil and switch to an analogue?

You can switch to analogue at any time. This will not affect the effectiveness of the main treatment in any way. NSAIDs are symptomatic therapy drugs, and they are only an adjunct against the background of the main treatment.

Sources of:

  1. Vidal. Reference book of medicines. Nimesil. https://www.vidal.ru/drugs/nimesil__2208
  2. Vidal. Reference book of medicines. Nemulex. https://www.vidal.ru/drugs/nemulex__28795
  3. Vidal. Reference book of medicines. Resulid. https://www.vidal.ru/drugs/resulide-tab
  4. Vidal. Reference book of medicines. Aponil. https://www.vidal.ru/drugs/aponil__2944
  5. Vidal. Reference book of medicines. Prolid. https://www.vidal.ru/drugs/prolid__21106
  6. Vidal. Reference book of medicines. Nimesulide. https://www.vidal.ru/drugs/nimesulid-6

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