Contents
– Cardiomagnyl is a combination drug that contains acetylsalicylic acid (ASA) and a magnesium salt, – comments Candidate of Medical Sciences, cardiovascular surgeon Andrey Eroshenko. – According to the manufacturer, this combination is the most effective. Plus, the manufacturing company used a successful marketing move – it made tablets in the form of hearts. Patients remember this original pill very well and use this drug with more commitment and interest than others.
Cardiomagnyl prevents the formation of blood clots and reduces blood viscosity. The official instructions for the drug say that magnesium reduces the negative effects of acetylsalicylic acid on the gastric mucosa.
The drug is used to prevent thrombosis in people with diseases of the heart and blood vessels. Among the indications for the use of Cardiomagnyl are angina pectoris, prevention of recurrent myocardial infarction and ischemic stroke.1. In addition, the drug is prescribed for the prevention of cardiovascular diseases in the elderly and from the “risk group”: with diabetes mellitus, hypertension, atherosclerosis, obesity1.
Cardiomagnyl has contraindications, including:
- hypersensitivity to ASA;
- bleeding tendency;
- severe violations of the liver and kidneys;
- erosive and ulcerative diseases of the gastrointestinal tract;
- pregnancy (except for a few weeks in the 2nd trimester);
- lactation period;
- children up to 18 years1.
Cardiomagnyl is suitable for long-term use. The standard dosage regimen is 1 tablet 1 time per day.
List of top 10 inexpensive and effective analogues of Cardiomagnyl according to KP
Together with an expert, we have selected the best analogues of Cardiomagnyl, which can be purchased at pharmacies. The list of analogues includes drugs with the same active ingredients (acetylsalicylic acid plus magnesium), mono-preparations based on ASA, as well as antiplatelet agents that contain other active ingredients, but have a similar therapeutic effect.
Cardiomagnyl and many of its analogues are available without a prescription, however, this does not mean that drugs can be taken uncontrollably. The best solution is to consult a doctor before buying an analogue of Cardiomagnyl.
1. Magnicardil
This is an analogue of Cardiomagnyl with a similar name. The composition of the drug contains acetylsalicylic acid and magnesium hydroxide2. The dosage also coincides, since the manufacturer produces two types of tablets:
- containing 75 mg of ASA and 15,2 mg of magnesium hydroxide;
- containing 150 mg of ASA and 30,39 mg of magnesium hydroxide.
Indications, contraindications and scheme of application are identical to Cardiomagnyl. The package of the drug may contain 30 or 100 tablets.
2. Kardevit-AS
As part of Kardevit-AS tablets – acetylsalicylic acid (at a dosage of 75 mg or 150 mg) in combination with magnesium hydroxide3. This is a complete analogue of Cardiomagnyl, the difference lies only in the set of excipients and the form of tablets. As for indications and contraindications, they coincide with Cardiomagnyl.
Kardevit-AS is available in a package that can contain from 10 to 600 tablets.
3. Sanovask
Sanovask is the next in the list of analogues of Cardiomagnyl. This is a single drug that contains only acetylsalicylic acid and is available in enteric-coated tablets.4. In addition to tablets with a standard dosage of 50 and 100 mg, the manufacturer offers another option – tablets with a dosage of 75 mg4. Indications, contraindications and method of application for Sanovask are the same as for Cardiomagnyl.
Sanovask is sold in packs containing 30, 60 and 100 pieces.
4. ASK-Cardio
Monopreparation based on ASA at a dosage of 100 mg5. Available in enteric coated tablets5. It is prescribed for the same indications as Cardiomagnyl. Contraindications and regimen also coincide.
The manufacturer produces 15 packaging options. The minimum number of tablets in a package is 7, the maximum is 140.
5. Plavix
This drug from the group of antiplatelet agents is an effective substitute for Cardiomagnyl. The active substance of Plavix is clopidogrel, which is close to acetylsalicylic acid in its ability to thin the blood, but does not irritate the gastric mucosa.
Plavix prevents platelets from sticking together and from forming blood clots in the arteries and veins. The drug helps prevent thrombosis in patients with ischemic stroke, myocardial infarction, acute coronary syndrome and some other cardiovascular diseases.6. It is recommended to take Plavix 1 time per day, regardless of the meal.
Contraindications for use: hypersensitivity to the components, pregnancy and lactation, acute bleeding, age up to 18 years, severe liver failure6.
Release form Plavix – tablets containing 75 or 300 mg of clopidogrel. The package can be 10, 28 and 100 pieces.
6. Clopidogrel
This is a Russian generic Plavix with an identical active ingredient – clopidogrel. Available in tablets with a dosage of 75 mg7. It is prescribed for the same indications as Plavix, can be used together with acetylsalicylic acid preparations. Clopidogrel has the same contraindications as Plavix.
On sale there are 3 packaging options – 14, 28 and 90 tablets.
7. Pletal
This is an original drug with the active ingredient cilostazol, which has an antiplatelet effect – it prevents the formation of blood clots, thins the blood and reduces inflammation in the vessels. Indications for use: intermittent claudication, peripheral circulatory disorders, vascular obstruction of the upper and lower extremities, postoperative period after stenting8.
Contraindications: renal, hepatic and heart failure, pregnancy and lactation, hypersensitivity to components, age up to 18 years8.
Pletal is available in tablets with a dosage of 100 mg.
8. Pletax
Pletax is a generic of Pletal and a possible substitute for Cardiomagnyl. The active ingredient of the drug is cilostazol at a dosage of 50 and 100 mg.9. Pletax is prescribed for the same indications as Pletal, primarily for the symptomatic treatment of intermittent claudication. Contraindications for drugs are identical.
Pletax is available in packs of 30 to 84 tablets.
9. Thrombo-ASS
Unlike Cardiomagnyl and its full analogues, this is a mono-drug with the only active ingredient – acetylsalicylic acid. Magnesium is absent. Thrombo-ASS tablets are enteric-coated and contain ASA at a dosage of 50 or 100 mg.10. Thrombo-ASS is prescribed for the same indications as Cardiomagnyl: for angina pectoris, for the prevention of recurrent myocardial infarction and ischemic stroke, for the prevention of thrombosis after operations on the heart and blood vessels10.
Thrombo-ASS is taken 1 time every day or every other day, 30 minutes before meals. It is recommended to take the tablets with plenty of water. The drug is intended for long-term use, the duration of therapy is determined by the doctor.
Contraindications for use are practically the same as for Cardiomagnyl: intolerance to ASA, severe renal and hepatic insufficiency, bleeding tendency, erosive and ulcerative pathologies of the gastrointestinal tract, chronic heart failure, pregnancy and lactation, age up to 18 years10.
10. CardiASK
Another analogue of Cardiomagnyl based on ASA. Release form – tablets that contain 50 or 100 mg of acetylsalicylic acid and are enteric-coated11. Indications for use and contraindications for the drug are the same as for Cardiomagnyl. The regimen also coincides – 1 time per day before meals, drinking plenty of liquid.
The drug is available in a package with a different number of tablets – 10, 20, 30, 60 and 90 pieces.
How to choose an analogue of Cardiomagnyl
– As substitutes for Cardiomagnyl, full analogues or monopreparations based on acetylsalicylic acid can be considered. One of the most popular monopreparations is Thrombo-ASS. In addition to it, there are many other drugs that contain low doses of ASA – from 75 to 375 mg, – comments Andrey Eroshenko, Ph.D., cardiovascular surgeon.
ASA-based preparations are of two types – with a conventional and enteric coating. It is believed that enteric-coated tablets have the advantage that they transfer the active substance to the intestines and therefore do not irritate the gastric mucosa. On the other hand, the damaging effect of acetylsalicylic acid is manifested when it is absorbed into the blood, so the transport of ASA to the intestine theoretically does not prevent adverse effects on the gastric mucosa. So the choice of a specific drug among enteric and conventional forms can be difficult.
If we are talking about other drugs from the group of antiplatelet agents, then the closest in properties to ASA is clopidogrel (the original drug based on clopidogrel – Plavix). It also causes blood thinning, but does not irritate the gastric mucosa. Usually, clopidogrel is prescribed instead of acetylsalicylic acid when the patient has a predisposition to gastric ulcer, and sometimes together with it, if endovascular intervention is performed: stenting of the heart vessels or peripheral arteries.
Another drug similar in action is Pletal. Widely used in vascular surgery, cardiology and neurology for the treatment of patients. Pletal has not only a blood-thinning, but also a pronounced anti-inflammatory effect, which is a very valuable property in the treatment of atherosclerosis, including diabetes. More affordable analogues of Pletal are Pletax and Aducil.
Reviews of doctors about the analogues of Cardiomagnyl
Cardiomagnyl and its analogues are widely used in medical practice. Monopreparations based on ASA are cheaper than Cardiomagnyl and are often used as substitutes. At the same time, doctors note that their bioavailability is slightly lower, and the irritating effect on the gastrointestinal mucosa is higher. Therefore, Cardiomagnyl is more suitable for long-term therapy.
As for antiplatelet agents with other active ingredients, in some cases they will be more effective than Cardiomagnyl. For example, Clopidogrel is the drug of choice for the prevention of complications in patients after a heart attack and stroke, and Pletax is for intermittent claudication.
Popular questions and answers
We asked the most popular questions about Cardiomagnyl analogues to our expert – Ph.D., cardiovascular surgeon Andrey Eroshenko.
When can analogues of Cardiomagnyl be used?
What happens if you stop taking Cardiomagnyl and switch to an analogue?
Sources of:
- Vidal. Reference book of medicines. Cardiomagnyl. https://www.vidal.ru/drugs/cardiomagnyl-1
- Register of medicines of Russia. Magnicardil. https://www.rlsnet.ru/drugs/magnikardil-86432
- Vidal. Reference book of medicines. Kardevit-AS. https://www.vidal.ru/drugs/kardevit-as
- Vidal. Reference book of medicines. Sanovask. https://www.vidal.ru/drugs/sanovasc
- Vidal. Reference book of medicines. ASK-Cardio. https://www.vidal.ru/drugs/asa-cardio__13224
- Vidal. Reference book of medicines. Plavix. https://www.vidal.ru/drugs/plavix__29665
- Vidal. Reference book of medicines. Clopidogrel. https://www.vidal.ru/drugs/clopidogrel__21851
- Braided. Instructions for use. https://transfarma.org/pletal.html
- Vidal. Reference book of medicines. Pletax. https://www.vidal.ru/drugs/pletax
- Vidal. Reference book of medicines. Thrombo-ASS. https://www.vidal.ru/drugs/thrombo_ass__863
- Register of medicines of Russia. Cardiask. https://www.rlsnet.ru/drugs/kardiask-25609
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