Thrombosis – a lot has been said about this disease recently, mainly due to the potential link with AstraZeneki vaccination against COVID-19. While there is no evidence of a direct relationship between thrombosis and vaccine use, it is important to know that the disease can be a side effect of many other medications.
- Many countries have suspended vaccination against COVID-19 with AstraZeneki over suspicions that the vaccine may cause blood clots in vaccinated people
- On March 18, the European Medicines Agency officially announced that the vaccine is safe and cannot be associated with an increased risk of thrombosis
- However, it is worth knowing that there is a large group of drugs where the manufacturers clearly indicate that their risk of blood clots increases
- These are primarily contraceptives, but not only. Here are some examples.
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- You can find more such stories on the TvoiLokony home page
Thrombosis as a side effect: Yasmin
Yasmin is one of the most popular contraceptive pills. The information about the risk of thrombosis appears right at the beginning of this leaflet, as is the case with other agents that work.
«Important information about combined contraceptive drugs
– They slightly increase the risk of a blood clot in the veins and arteries, especially in the first year of use, or when restarting after a break of 4 weeks or more ».
The thrombosis warnings and explanations form a very large part of this leaflet.
How often can thrombosis occur? “Within a year, about 9 to 12 out of 10 women who use a combined hormonal contraceptive containing drospirenone, such as Yasmin, will develop blood clots,” reads the leaflet.
Thrombosis as a side effect: Liberelle
The same applies to another contraceptive – Liberelle.
“The use of combined hormonal contraceptives, such as Liberelle, is associated with an increased risk of developing a blood clot, compared to if the treatment is not used”, says the manufacturer.
Read on in this leaflet that 5-7 out of 10 women may experience blood clots when using the hormonal contraceptive Liberelle. The ratio for women who do not take these drugs is 2 in 10.
- Also read: EMA – AstraZeneca vaccine is safe and effective
Thrombosis as a side effect: Harmonet
Another drug with a similar warning is Harmonet.
«Using a combined hormonal contraceptive like Harmonet increases the risk of developing a blood clot compared with not using it. In rare cases, a blood clot can block blood vessels and cause serious problems.
In rare cases the effects of a blood clot may be permanent or, very rarely, fatal » – we read.
The risk of a blood clot with HARMONET is slightly higher than with LIberelle.
- AstraZeneca COVID-19 vaccine and the risk of thrombosis. Three important facts
“Within a year, about 9 to 12 out of 10 women who use a gestodene-containing combined hormonal contraceptive, such as Harmonet, will develop a blood clot,” reads the report.
Thrombosis as a side effect: Vibin
Thrombosis as a side effect can also be found in the Vibin package insert,
«Using a combined hormonal contraceptive like Vibin increases the risk of developing a blood clot compared with not using it. In rare cases, a blood clot can block blood vessels and cause serious problems ».
The risk of blood clots when using Vibin is estimated at 9-12 cases per 100. women.
Thrombosis as a side effect: Metypred
Metypred is not a contraceptive. It has an immunosuppressive and anti-inflammatory effect, it is used, among others, in in gastroenterology, dermatology, hematology, allergology and rheumatology.
- Thrombosis. How is it related to COVID-19 and the AstraZeneki vaccine? The doctor explains
The package insert for the 16 gram tablet states that “The blood may increase clotting, which creates a risk of thrombosis” and “Other adverse cardiovascular effects associated with treatment with methylprednisolone include an increased risk of atherosclerosis, thrombosis and vasculitis”.
However, the possible frequency of these effects is not given.
Thrombosis as a side effect: Raloxifene
Raloxifene is also not a contraceptive, it is a drug used to treat and prevent osteoporosis in postmenopausal women.
In the package leaflet for Raloxifene Teva 60 mg, “Venous Thromboembolic Events” is listed first in the list of possible side effects.
Further in this leaflet you will find information about the frequency of such actions.
“Not so often: venous thromboembolic events, including deep vein thrombosis, pulmonary embolism, retinal vein thrombosis, superficial thrombophlebitis, arterial thromboembolism ».
‘Uncommon’ is defined as between 1 in 1000 and 1 in 100.
It should also be remembered that thromboembolism is caused by a gene mutation that may cause miscarriage in the second and third trimesters of pregnancy. For this reason, we offer thromboembolism diagnostics available on Medonet Market.
This may interest you:
- Should I get vaccinated with AstraZeneka? Can I have a different vaccine? The doctor explains
- Poland in 5th place in the world in the number of deaths. There are two reasons
- Side effects of the vaccine. When to see a doctor?
- Where can I get vaccinated against COVID-19? List of vaccination points
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